Junior/Assistant/Associate/Full Specialist - Sneddon Lab
The Department of Cell and Tissue Biology is seeking a highly motivated full-time non-faculty Academic Specialist to join The Sneddon Lab. Selected candidates will be appointed at the level of Junior, Assistant, Associate or Full Specialist depending on qualifications.
Founded in 1881, the UCSF School of Dentistry has striven to educate the leading practitioners, scholars and faculty members of the next generation. As a leading institution of oral and craniofacial health, our educational programs have grown to include, in addition to our DDS programs, an array of PhD, post-graduate and residency programs. Our student dentists, residents and faculty handle over 120,000 patient visits a year in our comprehensive UCSF Dental Center, and our students staff numerous community-based externship sites. The school is one of the top oral and craniofacial research enterprises in the world, ranked the top dental school in the country in research funding from the National Institutes of Health for 25 years, and home to several leading translational research programs.
The Department of Cell and Tissue Biology (CTB) is a basic science department within the School of Dentistry. The department was established in 2005 and includes 15 faculty with primary appointments and five faculty with secondary appointments. Additionally, the department is home to numerous postdoctoral fellows as well as graduate students in programs ranging from Biomedical Sciences, Tetrad and Biophysics to Developmental & Stem Cell Biology and Oral & Craniofacial Sciences. Faculty research interests include cell biology mechanisms relevant to cytoskeletal dynamics, development, metabolism, cancer, immunology and neurobiology.
Description:
The primary focus of the Sneddon laboratory is pancreatic development and type 1 diabetes, and we employ the tools of stem cell biology, developmental biology, genomics, and tissue engineering. The candidate will be expected to contribute to ongoing work in these areas, with specific duties including human embryonic stem cell culture, mouse husbandry and transplantations, FACS analysis, and genomics techniques. The position represents an opportunity to be at the cutting edge of translational research in a highly collaborative scientific environment.
Additionally, the specialist will be expected to assist with managing day-today lab operations, perform general lab duties, and act as a supportive and positive lab citizen.
Please apply online at https://aprecruit.ucsf.edu/JPF04439
Junior/Assistant/Associate/Full Specialist – Feinberg Lab
The Feinberg lab is seeking a Junior/Assistant/Associate/Full Specialist to join our group and contribute to new and ongoing projects. Our lab focuses on sensorimotor integration in mice. The candidate will be expected to assist graduate students and postdoctoral fellows in performing behavioral experiments in mice. Responsibilities may include performing stereotaxic surgeries to deliver viruses and drugs to specific anatomic sites in the mouse brain; performing two-photon calcium imaging in the brains of awake, behaving mice; performing immunostaining of brain slices to characterize gene expression in the nervous system; running behavioral assays in conjunction with optogenetics or in vivo calcium imaging; genotyping and mouse colony maintenance and perform other duties as assigned. Additionally, the specialist will be expected to assist with managing day-to-day lab operations, and perform general lab duties and be a positive lab citizen.
Required Qualifications:
• Excellent organizational and interpersonal communication skills (verbal and written)
• Willingness and ability to learn new methods and skills for changing research priorities.
• Ability to work independently and as a member of a research team.
• Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
• Must have (or be in process of obtaining) a bachelor’s degree (or equivalent degree) or four years of research experience to be appointed at the Junior rank.
• Must have (or be in process of obtaining) either a Master’s degree or a Bachelor’s degree with 3+ years of research experience to be appointed at the Assistant rank.
• Must have (or be in process of obtaining) a master’s degree (or equivalent degree) or five to ten years of research experience to be appointed at the Associate rank.
• Must have (or be in process of obtaining) a terminal degree (or equivalent degree) or at least ten or more years of research experience to be appointed at the Full rank.
Preferred Qualifications:
• Prior experience in handling mice and stereotaxic procedures
• Prior experience in analyzing experimental data in MATLAB and/or Python.
We are seeking at least a 1-year commitment. Depending on performance and workload, opportunities for independent research, mentorship of other trainees, and scientific writing will be available.
Applicants must meet requirements by the time of appointment.
Please apply online at https://aprecruit.ucsf.edu/JPF04418
Junior or Assistant Specialist - Roose Lab
The Roose lab is seeking a Junior or Assistant Specialist to join our group and contribute to new and ongoing projects. The Roose lab focuses on understanding cell fitness and cell fate decisions driven by cell-cell interactions and signaling pathways, in the context of stem cell biology, cancer, and autoimmune diseases. In our leukemia work, we focus on developing a new in vitro system so that we can grow (and developmentally track) human leukemias and explore therapy development.
The candidate will be expected to contribute to this new in vitro system, termed bone marrow organoids. The work will have very stong emphasis on hydrogel strategies and other bioengineering technologies to develop bone marrow organoids, but also cell culture of leukemia cell lines, primary leukemia cultures, imaging, and spectral flow. An exceptional candidate will lead their own independent project, develop new ideas, be familiar with the literature, and write up results and generate figure panels. Additionally, the specialist will be expected to assist with managing day-to-day lab operations, and perform general lab duties and be a positive lab citizen.
Required Qualifications:
- Must have (or be in process of obtaining) a bachelor’s degree (or equivalent degree) or four years of relevant research experience to be appointed at the Junior rank.
- Must have (or be in process of obtaining) a master’s degree or a baccalaureate degree with 3 or more years of research experience
- Experience with cell and tissue culture is a must. Affinity with tissue engineering, biomaterials and biomaterials processing is preferred.
- Excellent organizational and interpersonal communication skills (verbal and written).
- Willingness and ability to learn new methods and skills for changing research priorities.
- Ability to work independently and as a member of a multidisciplinary team with researchers at various academic levels.
- Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
Preferred Qualifications:
- Prior experience in synthesis of polymers, photo-responsive hydrogels (syntetic and natural derived or inspired), and cell encapsulation.
- Prior experience with biomaterials processing, in particular additive and layer-less printing techniques.
- Experience with imagine modalities such as uCT scan, confocal and bright field microscopy is desired.
We are seeking at least a 1-year commitment. Depending on performance and workload, opportunities for independent research, mentorship of other trainees, and scientific writing will be available.
Applicants must meet requirements by the time of appointment.
Please apply online at https://aprecruit.ucsf.edu/JPF04496
Junior/Assistant/Associate/Full Specialist - Roose Lab
The Roose lab is seeking a Junior/Assistant/Associate/Full Specialist to join our group and contribute to new and ongoing projects. Our lab focuses on cell-cell interactions and cell fate decisions in the context of immunology, cancer biology, and stem cell biology. In many projects we apply the use of organoids, generated in the Roose Organoid Disease-to biology (D2B) unit from patient material. We biobank and characterize epithelial cell organoids – often combined with other cell types - with imaging, spectral flow, and single cell technologies.
The candidate will be expected to contribute to generation and characterization of patient organoids in the Roose lab and Roose Organoid D2B unit, by conducting tissue culture and cell biology techniques, including organoid-immune cell co-cultures, imaging-, molecular- , and spectral flow- assays. An exceptional candidate will eventually lead their own independent project, develop new ideas, be familiar with the literature, and participate in procurement of funds, where appropriate. Additionally, the specialist will be expected to assist with managing day-to-day lab operations, and perform general lab duties and be a positive lab citizen.
Required Qualifications:
• Excellent organizational and interpersonal communication skills (verbal and written)
• Willingness and ability to learn new methods and skills for changing research priorities.
• Ability to work independently and as a member of a research team.
• Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
• Must have (or be in process of obtaining) a bachelor’s degree (or equivalent degree) or four years of research experience to be appointed at the Junior rank.
• Must have (or be in process of obtaining) a master’s degree (or equivalent degree) or at least five to ten years of research experience to be appointed at the Assistant or Associate ranks.
• Must have (or be in process of obtaining) a terminal degree (or equivalent degree) or at least ten or more years of research experience to be appointed at the Full rank.
Preferred Qualifications:
• Prior experience with tissue culture, aseptic techniques
• Prior experience in molecular biology (DNA cloning, PCR, etc.)
• Prior experience in computational analysis (data set analyses, statistics)
• Prior experience with software platforms (Microsoft office, Adobe stock)
Ideally, we are seeking at least a 2-year commitment. Depending on performance and workload, opportunities for independent research, mentorship of other trainees, and scientific writing will be available.
Please apply online at https://aprecruit.ucsf.edu/JPF04002
Junior/ Assistant Specialist - Liao Lab
The Department of Dermatology is seeking a Junior or Assistant Specialist in the Liao Lab. We are a basic genomics laboratory that studies how the skin and immune system functions in human tissues. The position will consist of bioinformatics analysis and wet lab experiments. This individual will be responsible for applying bioinformatic and machine learning techniques to genomic data, which will generated through RNA-seq and proteomics experiments.
Appointees in the Specialist series will be expected to engage in specialized professional activities and do not have teaching responsibilities. Specialists are expected to use their professional expertise to make scientific and scholarly contributions, and may participate in University and Public Service. Specialists appointed at the junior rank must possess a baccalaureate degree (or equivalent degree) or at least four years of equivalent research experience (e.g., with instrumentation and research equipment, social science research methods, or creative activities). Specialists appointed at the Assistant rank must possess a master’s degree (or equivalent degree) or at least five years of experience demonstrating expertise in the relevant specialization. A 22-month commitment to working in the lab is also required, but the position is open for longer term employment. Candidates must meet all required qualifications at the time of appointment. Candidate's CV must state basic qualifications (or if pending) upon submission. The position funding will end June 30, 2024.
Screening of applicants will begin immediately and will continue as needed throughout the recruitment period. Salary and rank will be commensurate with the applicants experience and training. Please apply online at https://aprecruit.ucsf.edu/JPF04096
Junior/Assistant/Associate/Full Specialist - Mukherjee Lab
The candidate will be responsible for laboratory research duties as well as lab management duties. This position will involve experiments including bacterial culture, mammalian cell culture, macrophage infections, microscopy, molecular biology, gene expression analysis, mammalian cell transfections, immunoprecipitations, protein gels, Western blotting; and perform other duties such as lab ordering/organization. The specialist will perform experiments with the bacterial pathogen Legionella pneumophila. General lab managerial tasks such as cataloging and ordering reagents are part of the position, and other duties as assigned. In addition independent research projects are available separate from the above describe duties. The Mukherjee lab is a highly collaborative space that is pushing the cutting edge of host-pathogen biology. Additionally, the specialist will be expected to assist with managing day-to-day lab operations, and perform general lab duties and be a positive lab citizen.
Required Qualifications:
• Excellent organizational and interpersonal communication skills (verbal and written)
• Willingness and ability to learn new methods and skills for changing research priorities.
• Ability to work independently and as a member of a research team.
• Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
• Must have (or be in process of obtaining) a bachelor’s degree (or equivalent degree) or four years of research experience to be appointed at the Junior rank.
• Must have (or be in process of obtaining) either a Master’s degree or a Bachelor’s degree with 3+ years of research experience for appointment to the Assistant rank.
• Must have (or be in process of obtaining) a master’s degree (or equivalent degree) or at least five to ten years of research experience to be appointed at the Associate rank.
• Must have (or be in process of obtaining) a terminal degree (or equivalent degree) or at least ten or more years of research experience to be appointed at the Full rank.
Preferred Qualifications:
• Prior experience with handling pathogenic microbes, aseptic techniques
• Prior experience in the design and assembly of DNA constructs
We are seeking at least a 2-year commitment. Depending on performance and workload, opportunities for independent research, mentorship of other trainees, and scientific writing will be available.
Applicants must meet requirements by the time of appointment.
Please apply online at https://aprecruit.ucsf.edu/JPF04433
Junior/Assistant/Associate/Full Specialist - Sil Lab
The Sil lab is seeking a Junior/Assistant/Associate/Full Specialist to join our group and contribute to new and ongoing projects. Our lab focuses on the basic biology of fungal pathogens and their interaction with innate immune cells. We are interested in understanding how these pathogens respond to their environment and how they manipulate the immune system. We take a number of molecular approaches, including genetics and genomics. The candidate will be expected to generate genetic tools and conduct microbiology and molecular biology techniques, including fungal and macrophage manipulation, cloning, protein purification, and biochemical assays. An exceptional candidate will lead their own independent project, develop new ideas, be familiar with the literature, and participate in procurement of funds, where appropriate. Additionally, the specialist will be expected to assist with managing day-to-day lab operations, and perform general lab duties and be a positive lab citizen.
Required Qualifications:
- Excellent organizational and interpersonal communication skills (verbal and written)
- Willingness and ability to learn new methods and skills for changing research priorities.
- Ability to work independently and as a member of a research team.
- Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
- Must have (or be in process of obtaining) a bachelor’s degree (or equivalent degree) or four years of research experience to be appointed at the Junior rank.
- Must have (or be in process of obtaining) a master’s degree or a baccalaureate degree with three or more years of research experience to be appointed at the Assistant rank.
- Must have (or be in process of obtaining) a master’s degree (or equivalent degree) or five to ten years of research experience to be appointed at the Associate rank.
- Must have (or be in process of obtaining) a terminal degree (or equivalent degree) or at least ten or more years of research experience to be appointed at the Full rank.
Preferred Qualifications:
- Prior experience with handling pathogenic microbes, aseptic techniques
- Prior experience in the design and assembly of DNA constructs
- Prior experience in molecular genetics and biology (i.e. gene knockouts, epitope tagging, immunoprecipitation, protein-protein interactions)
- Prior experience with RNAseq
- Prior experience with murine macrophage differentiation and infection
- Prior experience working with fungi
We are seeking at least a 2-year commitment. Depending on performance and workload, opportunities for independent research, mentorship of other trainees, and scientific writing will be available.
Applicants must meet requirements by the time of appointment.
Please apply online at https://aprecruit.ucsf.edu/JPF04646
Research Specialist – Rosenblum Lab
The Rosenblum Lab in the Department of Dermatology at UC San Francisco is seeking a Research Specialist at the Junior, Assistant, or Associate level. We are a basic immunology laboratory that studies how the immune system functions in both mouse and human skin. Our research focuses on regulatory T cells (Tregs), an immune cell type critical for preventing autoimmunity. We seek to understand how Tregs influence homeostasis, inflammation, tissue repair, and cancer by interacting with other immune cells, parenchymal cells, and stem cells in the skin.
This position requires a 2-year commitment and will consist of hands-on laboratory research (100% time commitment). Research will primarily involve assisting post-doctoral fellows, graduate students, and staff working on basic immunology projects, with the opportunity to learn skills such as mouse dissection, flow cytometry, confocal microscopy, CyTOF, bulk and single-cell RNA sequencing, and spatial transcriptomics. There will be opportunities to eventually drive/direct an independent research project.
Appointees in the Specialist series will be expected to engage full-time in research and professional activities and will not have teaching responsibilities. Specialists are expected to use their professional expertise to make scientific and scholarly contributions, and may participate in University and Public Service.
Specialists appointed at the Junior rank must possess a bachelor’s degree (or equivalent degree) or at least four years of equivalent research experience (e.g., with instrumentation and research equipment, social science research methods, or creative activities). Specialists appointed at the Assistant rank must possess a master’s degree or a bachelor’s degree with 3 or more years of research experience. Specialists appointed at the Associate rank must have a master’s degree (or equivalent degree) or five to ten years of research experience.
Screening of applicants will begin immediately and will continue as needed throughout the recruitment period. Optimal start date for the position is immediately. Please apply online at ###.
See Table 24B (https://www.ucop.edu/academic-personnel-programs/_files/2022-23/july-2022-salary-scales/t24-b.pdf) for the salary range for this position. A reasonable estimate for this position is $49,000-$79,300.
Please apply online at https://aprecruit.ucsf.edu/JPF04581
Junior Specialist – Oskowitz Lab
The Oskowitz lab at the University of California, San Francisco (UCSF) is seeking independent and creative researchers to join a fast-moving project developing a therapeutic for the treatment of aortic aneurysms. Funded by the National Institutes of Health (NIH) and the American Heart Association (AHA), the Oskowitz lab is focused on translational research for cardiovascular disease. The Oskowitz laboratory occupies approximately 1,000 sq. ft. on the 2nd floor of the Smith Cardiovascular Research Building (SCVRB) on the Mission Bay UCSF campus. The five story, SCVRB was opened in 2010 as the primary home of the UCSF Cardiovascular Research Institute investigators and is a state-of-the-art biomedical research facility. The top floor of SCVRB is a fully equipped vivarium including procedure and surgical suites. The lab has exclusive access to a small animal microsurgery suite on the 5th floor of the SCVRB.
In collaboration with the Principal Investigator, Dr. Adam Oskowitz and other senior scientists in the lab, the Specialist will focus on research investigating a treatment of abdominal aortic aneurysms. This will include basic molecular biology, cell culture, small animal surgery and in vivo work, large animal surgery and tissue acquisition. The Specialist will be integrated into a team of researchers focused on bringing a novel biotechnology from discovery to a first-in-human clinical trial and as such the work will have critical timelines and milestones.
Initially, the Specialist will work under direct supervision. After a period of onboarding, the Specialist may be given the opportunity for more independent research efforts depending on the level of competence and comfort. The Specialist will be expected to work onsite in the Oskowitz lab 5 days a week (Monday-Friday).
Specialists appointed at the Junior rank must have a baccalaureate degree (or equivalent degree) in biology, pharmacology, chemistry, bioengineering, or a related field or at least 4 years of experience with Molecular biology including RNA and protein-based assays animal models and in vivo work including tissue harvest, specimen collection, histology, and blood processing.
Specialist appointed at the Assistant rank must have a master’s degree (or equivalent degree) in biology, pharmacology, chemistry, bioengineering, or a related field or a baccalaureate degree with 3 or more years of years of experience with Molecular biology including RNA and protein-based assays animal models and in vivo work including tissue harvest, specimen collection, histology, and blood processing.
Specialist appointed at the Associate rank must have a master’s degree (or equivalent degree) in biology, pharmacology, chemistry, bioengineering, or a related field or at least 5 to 10 years of experience with Molecular biology including RNA and protein-based assays animal models and in vivo work including tissue harvest, specimen collection, histology, and blood processing.
Specialist appointed at the Full rank must have a PhD (or equivalent degree) in biology, pharmacology, chemistry, bioengineering, or a related field or at least 10 or more years of experience with Molecular biology including RNA and protein-based assays animal models and in vivo work including tissue harvest, specimen collection, histology, and blood processing.
Applicants who have significant experience with multi-channel flow cytometry or FACS, experience preforming small animal surgery or tissue harvest, experience with advanced microscopy and image analysis or experience with in vivo imaging or localization studies are strongly encouraged to apply.
See Table 24B for the salary range for this position. A reasonable estimate for this position is $49,000 - $173,900.
Please apply online at https://aprecruit.ucsf.edu/JPF04564.
Junior Specialist – Turnbaugh Lab
The Turnbaugh lab is seeking a Junior Specialist to join our group and contribute to new and ongoing projects. This work will focus on the study of the microbiome using Gnotobiotic mice, and will include performing advanced experimental techniques to execute experiments (for example, the Specialist may administer experimental agents via oral, i.p., or subcutaneous routes, and follow up with experimental disease scoring and tracking, dissection and processing of tissues, or other techniques deemed experimentally necessary). Lab techniques performed by the Specialist include (but are not limited to): DNA extraction, PCR, qPCR, microbial cultures, gram staining, and genotyping. The candidate will also be expected to contribute to novel projects advancing research and development of Gnotobiotic tools. For example, the candidate will work on the development of novel models (such as allergy and asthma) in sterile mice and the translation of embryo-transfer techniques into a germ-free setting, among other projects. An exceptional candidate will move these projects forward independently, helping the lab to develop and test new ideas. Additionally, the specialist will be expected to assist with managing day-to-day lab operations within the Gnotobiotic core facility, perform general lab duties, and be a positive lab citizen.
Required Qualifications:
• Excellent organizational and interpersonal communication skills (verbal and written)
• Willingness and ability to learn new methods and skills for changing research priorities.
• Ability to work independently and as a member of a research team.
• Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
• Must have (or be in process of obtaining) a bachelor’s degree (or equivalent degree) or at least four years of research experience to be appointed at the Junior rank.
Preferred Qualifications:
• Prior experience with handling pathogenic microbes, aseptic techniques
• Prior experience working in a research-based setting with murine models
• Prior experience in gnotobiotic mouse handling/maintenance in positive pressure isolators, with a focus on sterility
• Prior experience in advanced techniques in murine models (such as injection of compounds, oral gavage, anesthesia, surgery techniques and documentation)
We are seeking at least a 1-year commitment. Depending on performance and workload, opportunities for independent research, mentorship of other trainees, and scientific writing will be available.
Applicants must meet requirements by the time of appointment.
Please apply online at https://aprecruit.ucsf.edu/JPF04523, https://aprecruit.ucsf.edu/JPF03995, or https://aprecruit.ucsf.edu/JPF04669
Junior Specialist – Erlebacher Lab
The Junior Specialist will work in a basic/translational science laboratory on the UCSF Parnassus Campus that focuses on immunological and epigenetic features of pregnancy including why the fetus is not rejected by the maternal immune system, how labor induction is timed and controlled, and mechanisms of pregnancy complications (adrianerlebacherlab.org). Under the supervision of the PI, s/he will work independently on multiple projects and perform a variety of techniques, including:
1) Immunohistochemical and immunofluorescence staining of tissue sections, including photomicroscopy
2) Molecular biology techniques including RNA extraction, PCR, qPCR, RT-PCR, western blots, and PCR primer design using online programs
3) Cell culture, including cell transfections and treatments, and lentivirus preparation
4) Mouse colony maintenance, including tailing mice for genotyping, weaning of mouse litters, preparation of tail DNA and PCR analysis, and record keeping
5) Isolation of cells from mouse tissues, and their analysis by a variety of techniques, including flow cytometry and qRT-PCR.
The applicant must be able to perform detail-oriented tasks, manage multiple tasks at any one time, prioritize and perform experiments with minimal supervision, and have excellent organizational and communication skills.
Appointees in the Specialist series will be expected to engage in specialized research, professional activities and do not have teaching responsibilities. Specialists are expected to use their professional expertise to make scientific and scholarly contributions, and may participate in University and Public Service.
Required Experience, Skills:
Bachelor Degree in science or related majors, as well as familiarity with basic molecular biological, biochemical, and microbiological techniques. Candidates must meet the qualifications by the time of appointment. Candidate’s CV or cover letter must state required degree (or in process) upon submission.
Please apply online at https://aprecruit.ucsf.edu/JPF04041 with a CV, cover letter, and two references.
Junior Specialist – Chorba Lab
The Chorba Lab seeks a highly motivated Junior Specialist to work as a research technician and laboratory administrator. Under direct supervision and training, the Junior Specialist will work on several highly collaborative projects including 1) the role and druggability of the processing and trafficking pathways of PCSK9 in regulating the LDL receptor, 2) the characterization of CSDE1 as a regulator of LDLR mRNA decay, and 3) the development of methods to chemically perturb protein translation in a sequence specific manner. The incumbent for this position will have many duties relevant to these goals, including the generation of DNA constructs, generation and maintenance of cell lines, and production and purification of recombinant proteins, in addition to standard cell culture and molecular biology techniques. Responsibilities also include assisting with all routine laboratory maintenance (restocking of supplies, assisting with monitoring freezers, and additional duties as necessary). Notably, the successful candidate may be required to attend to cell culture samples or experimental procedures at off-hours or on weekends when necessary.
The successful candidate for this position will have a background in general biology, molecular biology, cell biology, genetics, and chemistry. They will be involved in analyzing the effects of chemical and biochemical perturbations of specific proteins both in vitro and in cells. This work will require a number of biochemical and biologic techniques including (but not limited to): PCR; DNA and protein gel electrophoresis; Western blotting; standard cell culture; flow cytometry; transfections; DNA/RNA extractions; protein purification; buffer preparation; and microplate assays. The candidate must have clear knowledge of molarity, sterile technique, standard Mendelian genetic inheritance, general microbiology, and the central dogma of molecular biology. Specialists appointed at the junior rank must possess a baccalaureate degree (or equivalent degree) or at least four years of relevant research experience (e.g., with instrumentation and research equipment, social science research methods, or creative activities).
Our research efforts are focused on identifying and validating drug targets and developing novel therapeutic strategies to treat cardiovascular disease, with a particular focus on regulators of lipid metabolism and cholesterol levels. To this end, we pursue the molecular mechanisms of how key players in these pathways interact, and how their dysregulation leads to disease. Our work bridges the interface of chemistry and biology, where we develop cutting-edge chemical, biochemical, and genetic tools to pursue our inquiries. We are an inclusive environment and are not afraid to think big.
Please apply online at https://aprecruit.ucsf.edu/JPF04472. Applicants’ materials must list current and/or pending qualifications upon submission.
Junior Specialist – Toczyski Lab
The Cancer Center is seeking a Junior Specialist. Responsibilities include general lab maintenance, including ordering supplies and upkeep. Performing and designing experiments, with frequent input from Dr. Toczyski and other members of the lab. These will involve both cell biological and biochemical experiments. Appointees in the Specialist series will be expected to engage in specialized research, professional activities and do not have teaching responsibilities. Specialists are expected to use their professional expertise to make scientific and scholarly contributions, and may participate in University and Public Service.
Required Qualifications:
• Specialists appointed at the junior rank must possess a baccalaureate degree (or equivalent degree) in Molecular Biology (or a related field) or must have at least four years of research experience (e.g., with instrumentation and research equipment, social science research methods, or creative activities).
• Undergraduates or work related molecular biology research experience required.
• Incumbent must have experience in lab maintenance, protein sample preparation and western blotting, cloning, protein purification, and tissue culture.
• All requirements must be met by the appointment date.
• Applicant’s materials must list (pending) qualifications upon submission.
Preferred Qualifications:
• Post-graduate training in field.
Please apply online at https://aprecruit.ucsf.edu/JPF04196.
Junior Specialist – Al-Sady Lab
The Al-Sady lab is seeking a Junior Specialist to join our group and contribute to new and ongoing projects. Our lab focuses on understanding the dynamics of repressive chromatin domains. We are particularly interested in the biochemical mechanisms my which “write” enzymes that depot reprseve hstone marks engage with their chromatin substrate and propagate repressive information along the chromosome. The candidate will be expected to contribute to the production and development of chromatin related tools for their project but also for other lab members and develop their own research project around the study of chromatin enzyme mechanisms. This will require cloning, bacterial expression, protein purification and enzymological and biochemical assays. An exceptional candidate will lead their own independent project, develop new ideas, be familiar with the literature, and participate in procurement of funds, where appropriate. Additionally, the specialist will be expected to assist with managing day-to-day lab operations, and perform general lab duties and be a positive lab citizen.
Required Qualifications:
• Excellent organizational and interpersonal communication skills (verbal and written)
• Willingness and ability to learn new methods and skills for changing research priorities.
• Ability to work independently and as a member of a research team.
• Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
• Must have (or be in process of obtaining) a bachelor’s degree (or equivalent degree) or four years of research experience to be appointed at the Junior rank.
Preferred Qualifications:
• Prior experience with handling protein prufication equipment such as FPLC or gravity columns
• Prior experience in the design and assembly of DNA constructs
• Prior experience with recombinant protein expression
• Prior experience with biophyisical approaches such as protein-protein interaction methods
• General familiarity with concepts in protein biochemistry
We are seeking at least a 1-year commitment. Depending on performance and workload, opportunities for independent research, mentorship of other trainees, and scientific writing will be available.
Applicants must meet requirements by the time of appointment.
See Table 24B (https://www.ucop.edu/academic-personnel-programs/_files/2022-23/july-2022-salary-scales/t24-b.pdf) for the salary range for this position. A reasonable estimate for this position is $49,000-$52,200.
Please apply online at https://aprecruit.ucsf.edu/JPF04476. Applicants’ materials must list current and/or pending qualifications upon submission.
Junior, Assistant, or Associate Specialist – Allen Lab
Area of Specialization / Responsibilities:
The Allen lab at UCSF is seeking applicants for a full-time position as a Junior/Assistant/Associate Specialist in our group. Our laboratory is engineering next-generation immune cells to tackle complex diseases such as cancer. We develop and apply new synthetic biology tools to reprogram how a patient’s immune cells (T cells, macrophages, etc …) process information, interact with each other, and execute anti-tumor functions. These tools allow us to interrogate tumor immunology with a unique “build to understand” mentality and to provide the tools to springboard to academic phase I clinical trials at UCSF.
Our research group interfaces closely with the UCSF Cell Design Institute and the Parker Institute for Cancer Immunotherapy, and candidates will participate in the dynamic academic environment of the greater UCSF cell therapy community. The selected candidate will perform laboratory and investigative procedures by conducting a variety of experimental techniques such as molecular cloning, cell culture (cell lines and primary cells), flow cytometry, CRISPR gene editing, and analysis of mouse tumor models. Technical training will be provided to complete these tasks, and the successful candidate must be able to learn new cell biological assays and execute them as necessary. The specialist will assist with ongoing experiments and to new research projects in development.
The Allen lab’s mission is to train the next generation of scientists under the mentorship of the lab’s Principal Investigator, Dr. Greg Allen, as well as additional members of the lab. Beyond training in technical skills, candidates will be provided with opportunities to present their research through research talks as well as co-authored publications.
Job responsibilities include but are not limited to:
• Applying a range of molecular biology techniques, including molecular cloning, and synthetic construct design.
• Performing flow cytometry and immunohistochemistry.
• Performing gene transfer studies using lentiviral infection of human cell cultures.
• Culturing primary immune cells and established cancer cell lines.
• Conducting studies of immune cell therapies against a variety of cancer cell lines in mice.
• High-dimensional analysis of mouse tumor specimens using spectral flow, CyTOF, or scRNAseq
• Assisting with lab maintenance duties, including ordering chemicals, reagents, supplies.
• Reading literature applicable to research areas as required
• Participating in laboratory meetings and planning
Required Qualifications
• Excellent organizational and interpersonal communication skills (verbal and written).
• Willingness and ability to learn new methods and skills for changing research priorities.
• Ability to work independently and as a member of a research team.
• Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
• Must have (or be in process of obtaining) a bachelor’s degree (or equivalent degree) or four years of research experience to be appointed at the Junior rank.
• Must have (or be in process of obtaining) a master’s degree (or equivalent degree) or a baccalaureate degree with 3 or more years of research experience to be appointed at the Assistant rank.
• Must have (or be in process of obtaining) a master’s degree (or equivalent degree) or at least ten years of research experience to be appointed at the Associate ranks.
• Prior experience working with biological samples in a laboratory setting
Preferred Qualifications
• Experience in basic aspects of biochemistry and cell biology including observing sterile technique for working with and passaging cell lines, counting cells, and preparing lysates.
• Willingness to work with laboratory mice.
• Experience with mammalian tissue culture and flow cytometry
• Computer software skills (MS Office, PRISM, Benchling, Flowjo, Illustrator)
• Able to learn complex tasks with general instruction. Able to use experience to perform a variety of new techniques.
A 2-year commitment is preferred. Depending on performance and workload, opportunities for independent research, mentorship of other trainees, and scientific writing will be available.
Applicants must meet requirements by the time of hire.
Applicants’ materials must list current and/or pending qualifications upon submission.
See Table 24B for the salary range for this position. A reasonable estimate for this position is $51,300-$82,100.
Please apply via AP Recruit at https://aprecruit.ucsf.edu/JPF04656.
Junior Research Specialist - Nayak Lab
The Nayak Lab (nayak.ucsf.edu) has an opening for a junior research specialist who is interested in advancing our knowledge of the gut microbiome and its impact on rheumatic diseases, such as rheumatoid arthritis. We use multiple state-of-the-art technologies, including bacterial genomics, metabolomics, anaerobic microbiology, bacterial genetics, gnotobiotic animal models, and studies of patient cohorts to elucidate the mechanisms by which gut microbiota impact patient response to treatment of rheumatic disease. A major driving force of the lab is the advancement of precision medicine for patients with rheumatic disease.
The candidate will contribute to new and ongoing projects in the lab. The candidate will use or learn a variety of techniques in anaerobic microbiology, microbial genomics, analytical chemistry, molecular biology, cell culture, mouse work, computational analysis, and immunology. Additionally, the specialist will be expected to assist with managing day-to-day lab operations, perform general lab duties, and be a positive lab citizen. Candidates will be expected to work independently and be active contributors to the collaborative multidisciplinary team of microbiologists, immunologists, and computational biologists. The successful candidate will report directly to Dr. Renuka Nayak, MD, PhD but will work closely with collaborators within and outside of the group. An exceptional candidate will lead their own independent project, develop new ideas, be familiar with the literature, and participate in procurement of funds, where appropriate. Candidates interested in pursuing MD, PhD, or MD/PhD. training will benefit most from this laboratory experience.
Required Qualifications:
• Excellent organizational and interpersonal communication skills (verbal and written).
• Willingness and ability to learn new methods and skills for changing research priorities.
• Ability to work independently and as a member of a research team.
• Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
• Familiarity with standard wet lab techniques (e.g. preparation of reagents/chemicals, basic microbiology, tissue culture, PCR, western blot, DNA/RNA purification) and/or computational analysis of large datasets.
• Must have (or be in process of obtaining) a bachelor’s degree (or equivalent degree) or four years of research experience.
Preferred Qualifications:
• Prior experience with handling pathogenic microbes, aseptic techniques
• Prior experience in high throughput sequencing and analysis
• Prior experience in mass spectrometry or other analytical chemistry approaches
• Prior experience in flow cytometry or other immune profiling methods
• Prior experience in the design and assembly of DNA constructs
• Prior experience in bacterial genome manipulation
• Prior experience working with mice
We are seeking at least a 2-year commitment. Depending on performance and workload, opportunities for independent research, mentorship of other trainees, and scientific writing will be available. Applicants must meet requirements by the time of appointment.
The Nayak Lab is located at the San Francisco VA Medical Center, perched atop Land’s End and overlooking the San Francisco Bay. We are a part of the University of California, San Francisco (UCSF) Benioff Center for Microbiome Medicine (BCMM), enabling engagement with a rich community of investigators and access to cutting-edge resources for promoting microbiome research.
Please apply online at https://aprecruit.ucsf.edu/JPF04699. Applicants’ materials must list current and/or pending qualifications upon submission.
See Table 24B for the salary range for this position. A reasonable estimate for this position is $51,300-$54,600.
Junior Specialist - Diaz lab
The Diaz lab in the UCSF Brain Tumor Center seeks a highly motivated individual for the position of Junior Specialist. Our lab studies primary brain tumors using genomics and molecular approaches. Under direct supervision and training, the Junior Specialist will become familiar with single-cell genomics assays, cell culture, and other molecular assays. Job responsibilities and opportunities include, but are not limited to, assisting with: cell culture, processing of clinical specimens, single-cell genomics assays, and day-to-day lab management activities.
This position requires analytical thinking, a strong commitment to our shared goals, attention to detail and accurate record keeping. BA/BS in the Biomedical Sciences or a Quantitative discipline by the start date. Applicant’s materials must list (pending) qualifications upon submission. This position is an excellent opportunity to gain experience in basic molecular and genomics skills in preparation for application to a PhD or MD program. Prior laboratory experience, familiarity with cellular and/or genomics assays, or bioinformatics/computational skills are preferred but not required.
Appointees in the Specialist series will be expected to engage in specialized research, professional activities and do not have teaching responsibilities. Specialists are expected to use their professional expertise to make scientific and scholarly contributions, and may participate in University and Public Service. Screening of applicants will begin immediately and will continue as needed throughout the recruitment period. Salary and rank will be commensurate with the applicants experience and training.
See Table 24B (https://www.ucop.edu/academic-personnel-programs/_files/2022-23/july-2022-salary-scales/t24-b.pdf) for the salary range for this position. A reasonable estimate for this position is $49,000 -$52,200.
Please apply online at https://aprecruit.ucsf.edu/JPF04102.
Junior/Assistant/Associate Specialist – Lakkaraju lab
The Department of Ophthalmology at the University of California, San Francisco, is currently accepting applications for a Junior/Assistant/Associate Specialist in the laboratory of Dr. Aparna Lakkaraju. Our research focuses on identifying pathological mechanisms and developing therapeutics for age-related macular degeneration (AMD), a complex neurodegenerative disease that destroys high-resolution central vision in over 50 million older adults. The candidate will join an interdisciplinary team of scientists to evaluate novel therapeutic targets in mouse models of disease.
This is a full-time position ideal for applicants interested in developing mouse models of disease to evaluate pathology and potential drug candidates. To learn about our science, visit: https://ophthalmology.ucsf.edu/lakkarajulab/
Responsibilities include the following:
- Manage transgenic mouse colonies, including breeding and genotyping.
- Perform routine biochemical, molecular biology, and confocal microscopy experiments.
- Design and execute studies in mouse models.
- Generate and maintain primary cell cultures.
- Perform data analysis, record keeping.
- Participate in grant and manuscript writing.
- Present findings at national and international meetings.
- Mentor trainees as needed.
Required Qualifications:
- Specialists appointed at the junior rank must possess (or in process of obtaining) a baccalaureate degree (or equivalent degree) in biological/biochemical science or related field or must have at least four years of research experience in a related field.
- Specialists appointed at the Assistant rank must possess (or in process of obtaining) a master’s degree (or equivalent degree) in biological/biochemical science or related field or must have a baccalaureate degree with three or more years of research experience.
- Specialists appointed at the Associate rank must possess (or in process of obtaining) a master’s degree (or equivalent degree) in biological/biochemical science or related field or must have at least five – ten years of experience in the relevant specialization.
- Appointees at the Associate level must have significant record of academic accomplishment including published or in-press publication, and a demonstrated record of university and/or public service.
- Applicants’ materials must list current and/or pending qualifications upon submission.
- Applicants must have obtained the degree requirement for the Specialist rank by the time of hire.
- Hands-on experience working with rodents.
- Proficiency in designing, executing, and analyzing in vivo experiments.
- Experience with standard molecular and cell biology techniques including cell culture, western blotting, microscopy, PCR, genotyping, cloning.
Preferred Qualification:
- Experience with ocular disease models is preferred.
Screening of applicants will begin immediately and will continue as needed throughout the recruitment period.
Salary will be commensurate with the applicants experience and training.
See Table 24B for the salary range for this position. A reasonable estimate for this position is $49,000 - $78,500.
Please apply online at https://aprecruit.ucsf.edu/JPF04548.
Junior/Assistant/Associate/Full Specialist - Larson Lab
The Larson lab is seeking a Junior, Assistant, Associate, or Full Specialist to work on the development of new advanced medical imaging technologies, which requires the development of specialized acquisition, reconstruction, and/or image analysis methods. These technologies are being applied broadly to improve patient care in the areas of prostate cancer, kidney cancer, metastatic cancer, heart diseases, kidney diseases, lung diseases, and neurodegenerative diseases. This candidate will also assist in the deployment and application of these methods into patient studies. They must be able to work and communicate well in a multi-disciplinary team.
Required Qualifications:
- Specialists appointed at the Junior rank must possess a bachelor’s degree (or equivalent degree) in Bioengineering, Electrical Engineering, Computer Science (or related discipline) or at least four years of research experience.
- Specialists appointed at the Assistant or Associate ranks must possess a master’s degree (or equivalent degree) or at least five years to ten years of research experience.
- Specialists appointed at the Full rank must possess a terminal degree (or equivalent degree) or ten or more years of research experience.
- Applicants must meet all the requirements by the time of hire.
- Candidate’s CV and/or cover letter must state qualifications (or if pending) upon submission.
Preferred Qualifications:
- Experience with Image visualization and image processing
- Scientific programming experience (e.g. Matlab and/or Python)
- Experience with medical images and data
- Software experience such as C++ or similar
- Machine Learning experience in PyTorch, TensorFlow or similar
- Basic knowledge of anatomy and physiology
- Able to perform scientific literature review
Screening of applicants will begin immediately and will continue as needed throughout the recruitment period. Salary and rank will be commensurate with the applicants experience and training.
See Table 24B (https://www.ucop.edu/academic-personnel-programs/_files/2022-23/july-2022-salary-scales/t24-b.pdf) for the salary range for this position. A reasonable estimate for this position is $49,000-$173,900.
Please apply online at: https://aprecruit.ucsf.edu/JPF04074 with cover letter, CV and statement of research.
Junior/Assistant/Associate/Full Specialist - Tymofiyeva Lab
The Tymofiyeva lab is looking for a Junior, Assistant, Associate, or Full Specialist who is enthusiastic and motivated to join our lab focused on adolescent neuroimaging and adolescent mental health. In particular, the successful candidate will be assisting with recruitment, MRI scans, and psychometric assessments of study participants, as well as with data analyses. In addition, the applicant will be expected to attend regular lab meetings and to perform additional duties in the lab as needed.
Required Qualifications:
- Specialists appointed at the Junior rank must possess a bachelor’s degree (or equivalent degree) in biology, biomedical imaging, psychology or related sciences or at least four years of research experience.
- Specialists appointed at the Assistant rank must possess a master’s degree (or equivalent degree) or a bachelor’s degree with three or more years of research experience.
- Specialists appointed at the Associate rank must possess a master’s degree (or equivalent degree) or five to ten years of research experience.
- Specialists appointed at the Full rank must possess a terminal degree (or equivalent degree) or ten or more years of research experience.
- Applicants must meet all the qualifications by the time of hire.
- Candidate’s CV and/or cover letter must state qualifications (or if pending) upon submission.
- One or more years of research work in the field of mental health of adolescents ages 14-18 with and without clinical diagnoses of depression and anxiety.
- One or more years of research work in the field of adolescent suicidality.
Preferred Qualifications:
- Training in administering Children's Depression Rating Scale-Revised (CDRS-R)
- Ability to organize data and keep detailed records
- Knowledge of the principles and procedures of at least one neuroimaging method (e.g., MRI, EEG, MEG) and excellent communication skills (both oral and written) in English
- Experience of scoring psychological assessments
- Neuroimaging data analysis skills
- Excellent organization skill and attention to detail
- Excellent time and task management skills
- Ability to work effectively in a team environment
- Ability to work independently and assess need for assistance from supervisor
Screening of applicants will begin immediately and will continue as needed throughout the recruitment period. Salary and rank will be commensurate with the applicants experience and training.
See Table 24B for the salary range for this position. A reasonable estimate for this position is $51,300-$181,800.
Please apply online at: https://aprecruit.ucsf.edu/JPF04585 with a cover letter and CV.
Junior or Assistant Specialist - Hernandez Lab
The Department of Bioengineering and Therapeutic Sciences is now recruiting a Junior or Assistant Specialist. The successful candidates will work in the field of population genetics, human genetics, computational/statistical genomics, or a related field. Projects will focus on a range of topics from modeling how evolutionary forces shape patterns of genetic variation to genetic architecture of complex traits to multi-omics analysis of complex diseases. Most work will be computational, though some opportunities for wet lab work will arise. This is primarily a training position. Successful candidates should be interested in exploring a research career. It is anticipated that the successful candidates will apply to graduate schools 1-2 years after joining our group.
Required Qualifications:
• Junior rank- possess a bachelor’s degree (or equivalent degree) or at least four years of relevant research experience.
• Assistant rank- possess a master’s degree (or equivalent degree) or five years of experience in the relevant specialization.
• Must be proficient in one or more programming languages (or excited to gain coding proficiency
• Have statistical training or eager to gain training in statistical thinking
• Have a background in genetics (or a related biological field) or be interested in learning about this field
• Have some prior exposure to computational research (at least 4 weeks in duration).
• Candidate’s must meet the required qualifications at the time of start.
• Candidate’s CV must state qualifications (or if pending) upon submission.
Preferred Qualifications:
• Candidates that are eligible to join the PROPEL training program (propel.ucsf.edu) are especially encouraged to apply.
Please apply online at https://aprecruit.ucsf.edu/JPF04239, with a CV, cover letter, and statement of research, and three reference contacts.
See Table 24B (https://www.ucop.edu/academic-personnel-programs/_files/2022-23/july-2022-salary-scales/t24-b.pdf) for the salary range for this position. A reasonable estimate for this position is $49,000-$63,000.