UCSF has several job titles/positions that work for postbac scholars. These include:
- Junior Specialist (or Assistant Specialist for scholars with more research experience)
- Staff Research Associate
- Research Assoiciate
- Clinical Research Coordinator (best suited for scholars with clinical aspirations, i.e. MD/PhD-bound scholars)
The job postings in the accordian below are for positions in PROPEL-affiliated labs. We recommend mentioning your interest in the PROPEL program in your cover letter when you apply to these positions.
For additional job postings (in both PROPEL and non-PROPEL affiliated labs) please search APrecruit using the keyword "junior" to pull up all junior specialist related positions. You can also search Brassring using the keyword "Staff Research Associate" or "Clinical Research Coordinator" (full time). The Gladstone is a UCSF affiliate institute located at Mission Bay. When searching the Gladstone Institute Career Page, look for "Research Associate" job postings.
PROPEL is a very large program, so we still recommend mentioning your interest in PROPEL in your cover letter to these non-PROPEL affiliated faculty* as it may still hold some sway. (*Any UCSF faculty can become PROPEL affiliated once they hire an eligible scholar and apply to the program.)
UCSF PROPEL is also proud to partner with other postbac programs at other universities. See our list of partners here for additional opportunities.
Cancer
Staff Research Associate - Sweet-Cordero Lab
The Sweet-Cordero laboratory is on the Mission Bay campus of UCSF. The laboratory focuses on molecular biology of cancer, with a particular focus on pediatric sarcomas and lung cancer. We are seeking a research assistant to work closely with a postdoctoral fellow on design and execution of experiments involving molecular biology, tissue culture and in vivo analysis using mouse models and human samples . Work will involve tissue culture, wet lab assays (western blotting, immunofluorescence, PCR), but will primarily focus on in vivo studies employing small animals (mice) – giving investigational treatments, performing imaging, and dissection. Some prior experience with mouse work is preferred, and a general willingness to work with live small animals (mice) is crucial. Attention to detail is also crucial as these are time sensitive and complex experiments. The current project focus is on an immuno-oncology treatment approach to pediatric osteosarcoma.
Staff research assistant will be supervised directly by pediatric oncologist who is passionate about cancer research and can provide career mentorship from the unique perspective of a physician-scientist. Opportunities for exploration of clinical patient care (shadowing, attending tumor boards, discussing clinical cases with direct research applications) may also be available. This job posting is well-suited for an individual with a background in laboratory research with interested in pursuing a career in medicine, MD/PhD, or MD physician scientist.
The final salary and offer components are subject to additional approvals based on UC policy.
Your placement within the salary range is dependent on a number of factors including your work experience and internal equity within this position classification at UCSF. For positions that are represented by a labor union, placement within the salary range will be guided by the rules in the collective bargaining agreement.
The salary range for this position is $26.00 - $31.04 (Hourly Rate).
To learn more about the benefits of working at UCSF, including total compensation, please visit: https://ucnet.universityofcalifornia.edu/compensation-and-benefits/index.html
Department Description
The Department of Pediatrics is one of the largest and most complex departments in the School of Medicine. The Department is comprised of 18 divisions employing over 400 core faculty. The Department ranks 21st in the nation among pediatric departments for funding from the National Institutes of Health.
Required Qualifications
- BA/BS in Biology, Molecular Biology or a related scientific field or equivalent combination of education and experience
- Must have 1 year experience in lab setting including molecular biology and tissue culture
- Must have excellent communication skills
- Must be willing to work with small animals (mice) and perform small animal surgeries
Preferred Qualifications
- Significant data management skills including advanced excel skills, preferably experience with other databases such as Filemaker, etc.
- Overall knowledge of lab organization
- Minimum of one (1) year of full-time prior lab experience
- Prior experience working with mice
Chemistry and Chemical Biology
Junior Specialist - Fujimori Lab
The appointed individual will be required to accurately document all experiments and will need to have excellent written and verbal communications. Candidates interested in obtaining research experience prior to applying to graduate school and those who prefer long term technician position are encouraged to apply.
Required Qualifications:
- A bachelor’s degree in biochemistry, chemistry, chemical biology or a related field or at least four years of research experience.
- Excellent ability to document experiments and to communicate (written and verbal)
- Prior research experience
- Ability to work as a member of a dynamic, interdisciplinary team
- Motivation for scientific research and strong work ethics
- Candidates must meet the required qualifications at the time of appointment.
- Candidate’s CV/cover must state required qualifications (or if pending) upon submission.
Preferred Qualifications:
- Research experience in chemical biology, biochemistry or chemistry
- One year of research experience in academia or industry
Please apply online at https://aprecruit.ucsf.edu/JPF05091, with a CV, cover letter, and two references.
See Table 24B for the salary range for this position. A reasonable estimate for this position is $51,300-$54,600.
Computational Biology/Medical Informatics
Junior/Assistant/Associate/Full Specialist - Larson Lab
The Larson Lab is seeking a Junior, Assistant, Associate, or Full Specialist. This position is focused on using modern machine learning and computer vision algorithms for automated large-scale analyses of cancer imaging data, working with Dr. Thomas Hope (https://profiles.ucsf.edu/thomas.hope) and Prof. Peder Larson (http://www.radiology.ucsf.edu/research/labs/larson).
More specifically, positron emission tomography (PET) with prostate-specific membrane antigen (PSMA) based agents is transforming the assessment of lethal advanced prostate cancers. UCSF and Dr. Thomas Hope have led the clinical translation of this agent, and a key next step is to develop advanced tools for analyzing PSMA PET data. This promises to maximize the utility by improving our understanding how the measurements in PSMA PET images in relation to diseases progression and treatments.
We propose to develop such advanced analysis tools using modern machine learning and computer vision methods to automatically segment and classify lesions as well as provide quantitative measures of localized disease burden.
The responsibilities of this position include:
- Curation and management of cancer imaging datasets
- Integration of information from clinical databases and clinicians
- Training machine learning models using cancer imaging datasets
Required Qualifications:
- Specialists appointed at the Junior rank must possess a baccalaureate degree in Computer Science, Electrical Engineering, Data Science, (or equivalent degree or related field) or at least four years of research experience.
- Specialists appointed at the Assistant rank must possess a master’s degree (or equivalent degree) or a baccalaureate degree with three or more years of research experience.
- Specialists appointed at the Associate rank must possess a master’s degree (or equivalent degree) or five to ten years of research experience.
- Specialists appointed at the Full rank must possess a terminal degree (or equivalent degree) or ten or more years of research experience.
- Must have strong written and verbal communication skills.
- Ability to work on collaborative research projects in a multi-disciplinary team.
- Applicants must meet all of the requirements by the time of hire.
- Applicant materials must list current and/or pending qualifications upon submission.
Preferred Qualifications:
- Experience with Python and PyTorch
- Setting up and curating large datasets
- Computer vision model development
- Training of Machine Learning models
- Training of Machine Learning models based on image data
See Table 24B for the salary range for this position. A reasonable estimate for this position is $51,300-$181,800.
Please apply online at: https://aprecruit.ucsf.edu/JPF05026 with a cover letter, CV, and contact information for two references.
Computational Research Associate - Corces Lab
This position will be research-based and fully computational with multiple opportunities for publication. The skills and experiences acquired from this position would provide a useful background for future pursuits in biological and/or medical graduate education and we place a strong emphasis on mentorship of the next generation of scientists. While prior laboratory experience is valuable, we place a greater emphasis on essential personal attributes such as organization, attention to detail, and communication skills. We have an established track record of helping young scientists achieve admission to graduate education programs and apply for and receive fellowships such as the National Science Foundation’s Graduate Research Fellowship Program.
More information about the laboratory and its current and past members can be found at www.corceslab.com
Duties & Responsibilities
For day-to-day activities, the candidate will be directly supervised by a senior member of the laboratory and will have weekly or bi-weekly meetings with the PI, Dr. Ryan Corces. They will participate in weekly lab meetings and journal clubs and have the freedom to set their own schedule (within reason). As part of the training environment that we provide, the candidate will be encouraged to participate in professional development activities not directly tied to their work such as attending seminars, conferences, workshops, etc. Remote/hybrid work is not permitted on a routine basis.
As noted above, direct prior experience in the relevant techniques is not required. We list below the types of activities one could expect to perform in this position:
- Single-cell analysis of gene expression and chromatin accessibility data
- Training and querying machine learning models to understand the impact of genetic variants
- Development of robust software and pipelines for use internally within the lab and for broad sharing with the research community
- Collaboration with wet-lab members of the lab to assist with data analysis of ‘omics datasets
- Routine laboratory management such as supply ordering, maintenance, and upkeep (5% of total effort)
Qualifications
- AA/AS and 2+ years of relevant experience or BA/BS in a relevant field
- Prior coding experience in R and/or Python
What we offer
- Targeted mentorship to help you achieve your goals, both during your tenure in the lab and beyond
- Training in how to think and communicate as a scientist
- Training in computational biology techniques in the fields of single-cell biology, genomics, neurobiology, and epigenomics
- Opportunities for scientific publication
- Access to Gladstone’s training classes and tools
- Access to Gladstone’s guest scientific lectures from world renowned professors
- Transparent and equitable pay based on Gladstone Institutes’ standardized policies
Hiring Range:
$56,163 ($27.00/hr) - $64,173 ($31.11/hr)
Developmental and Stem Cell Biology
Junior Specialist - Liu Lab
Description
The Liu lab is seeking a Junior Specialist to join our group and contribute to new and ongoing projects. Using Drosophila fruit flies as a model system, our lab studies the cellular and molecular basis of nutrient-specific appetite, and how these mechanisms contribute to diet-induced obesity and other metabolic disorders. The candidate will be expected to contribute to these research directions, by using techniques including fly genetics, microbiology, molecular biology, immunohistochemistry, neuronal imaging, behavioral analyses, etc. An exceptional candidate will lead their own independent project, be familiar with the literature, develop new ideas, and participate in procurement of funds, where appropriate. Additionally, the specialist will be expected to assist with managing day-to-day lab operations, and perform general lab duties and be a positive lab citizen. Depending on performance and workload, mentorship of other trainees, and scientific writing will be available.
Required Qualification (Applicants must meet requirements by the time of appointment):
- Excellent organizational and interpersonal communication skills (verbal and written)
- Willingness and ability to learn new methods and skills for changing research priorities.
- Ability to work independently and as a member of a research team.
- Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
- Must have (or be in process of obtaining) a bachelor’s degree (or equivalent degree) or four years of research experience to be appointed at the Junior rank.
We are seeking at least a 1-year, preferably 2-year commitment. We are committed to fostering a diverse, equitable, and inclusive workplace in our lab, and welcome applicants from underrepresented backgrounds to join us.
Please apply online at https://aprecruit.ucsf.edu/JPF04919
Junior Specialist – Erlebacher Lab
The Junior Specialist will work in a basic/translational science laboratory on the UCSF Parnassus Campus that focuses on immunological and epigenetic features of pregnancy including why the fetus is not rejected by the maternal immune system, how labor induction is timed and controlled, and mechanisms of pregnancy complications (adrianerlebacherlab.org). Under the supervision of the PI, s/he will work independently on multiple projects and perform a variety of techniques, including:
1) Immunohistochemical and immunofluorescence staining of tissue sections, including photomicroscopy
2) Molecular biology techniques including RNA extraction, PCR, qPCR, RT-PCR, western blots, and PCR primer design using online programs
3) Cell culture, including cell transfections and treatments, and lentivirus preparation
4) Mouse colony maintenance, including tailing mice for genotyping, weaning of mouse litters, preparation of tail DNA and PCR analysis, and record keeping
5) Isolation of cells from mouse tissues, and their analysis by a variety of techniques, including flow cytometry and qRT-PCR.
The applicant must be able to perform detail-oriented tasks, manage multiple tasks at any one time, prioritize and perform experiments with minimal surpervision, and have excellent organizational and communication skills.
Appointees in the Specialist series will be expected to engage in specialized research, professional activities and do not have teaching responsibilities. Specialists are expected to use their professional expertise to make scientific and scholarly contributions, and may participate in University and Public Service.
Required Experience, Skills:
Bachelor Degree in science or related majors, as well as familiarity with basic molecular biological, biochemical, and microbiological techniques. Candidates must meet the qualifications by the time of appointment. Candidate’s CV or cover letter must required degree (or in process) upon submission.
Screening of applicants will begin immediately and will continue as needed throughout the recruitment period. Salary and rank will be commensurate with the applicants experience and training.
Please apply online at https://aprecruit.ucsf.edu/JPF05387, with a CV, cover letter, and two references.
See Table 24B for the salary range for this position. A reasonable estimate for this position is $53,100-$56,600.
Junior Specialist - Liu Lab
Description
The Liu lab is seeking a Junior Specialist to join our group and contribute to new and ongoing projects. Using Drosophila fruit flies as a model system, our lab studies the cellular and molecular basis of nutrient-specific appetite, and how these mechanisms contribute to diet-induced obesity and other metabolic disorders. The candidate will be expected to contribute to these research directions, by using techniques including fly genetics, microbiology, molecular biology, immunohistochemistry, neuronal imaging, behavioral analyses, etc. An exceptional candidate will lead their own independent project, be familiar with the literature, develop new ideas, and participate in procurement of funds, where appropriate. Additionally, the specialist will be expected to assist with managing day-to-day lab operations, and perform general lab duties and be a positive lab citizen. Depending on performance and workload, mentorship of other trainees, and scientific writing will be available.
Required Qualification (Applicants must meet requirements by the time of appointment):
- Excellent organizational and interpersonal communication skills (verbal and written)
- Willingness and ability to learn new methods and skills for changing research priorities.
- Ability to work independently and as a member of a research team.
- Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
- Must have (or be in process of obtaining) a bachelor’s degree (or equivalent degree) or four years of research experience to be appointed at the Junior rank.
We are seeking at least a 1-year, preferably 2-year commitment. We are committed to fostering a diverse, equitable, and inclusive workplace in our lab, and welcome applicants from underrepresented backgrounds to join us.
*Please apply online at https://aprecruit.ucsf.edu/JPF04919 *
Junior Specialist - Selleri Lab
Under direct supervision of lab personnel, the Junior Specialist is assigned to assist in research activities in the lab focused on developmental biology, organogenesis, and mouse models of birth defects. The primary task will be to perform genotyping of mouse colonies and molecular cloning. Incumbent will verify results through molecular assays (PCR, qPCR, protein assay) and cell culture. Incumbent will assist in maintaining genetic modified mouse lines / colonies as well as common lab duties. This is a part-time position.
Key Responsibilities include the following skills:
- Molecular Cloning
- DNA and RNA extraction and purification.
- PCR and qPCR
- Western blotting, ELISA
- Assist in maintenance of mouse colonies
- Small animal handling, euthanasia, dissection, and organ harvesting
- Preparation and sectioning of frozen and paraffin-embedded tissues
- Chromogen and fluorescent immunohistochemistry and special histological stains
- Maintenance of mammalian cell culture and tissue culture
- Isolation of primary cells
Required Qualifications:
- Specialists appointed at the Junior rank must possess a baccalaureate degree (or equivalent degree) or at least four years of research experience.
Preferred Qualifications:
- Able and willing to assist lab members in their projects.
- Ability to learn new methods/techniques and apply them as needed.
- Ability to understand complex directions and protocols. Must also be willing to ask for assistance or further guidance when need arises.
- Strong computer skills using software programs such as MS Office. Candidate will need to manipulate spreadsheets and record data in various form.
- Computer skills using specialized software and programs for molecular cloning, e.g., Geneious and SnapGene.
- Ability to quickly perform mathematical calculations needed to make dilutions of stock chemical solutions.
- Possesses the attention to detail that is required to perform the daily procedures and lab activities.
- Excellent organizational skills and ability to display those talents in difficult situations.
- Ability to work with other labs and services to complete assigned tasks.
See Table 24B for the salary range for this position. A reasonable estimate for this position is $53,100-$56,600.
Please apply online at: https://aprecruit.ucsf.edu/JPF05451 with a cover letter, CV, and contact information for one reference. Applicant materials must list current and/or pending qualifications upon submission. The selected candidate must meet all of the qualifications at the time of appointment.
Junior/Assistant/Associate/Full Specialist - Sneddon Lab
The Department of Cell and Tissue Biology is seeking a highly motivated full-time non-faculty Academic Specialist to join The Sneddon Lab. Selected candidates will be appointed at the level of Junior, Assistant, Associate or Full Specialist depending on qualifications.
The Department of Cell and Tissue Biology (CTB) is a basic science department within the School of Dentistry. The department was established in 2005 and includes 15 faculty with primary appointments and five faculty with secondary appointments. Additionally, the department is home to numerous postdoctoral fellows as well as graduate students in programs ranging from Biomedical Sciences, Tetrad and Biophysics to Developmental & Stem Cell Biology and Oral & Craniofacial Sciences. Faculty research interests include cell biology mechanisms relevant to cytoskeletal dynamics, development, metabolism, cancer, immunology and neurobiology.
Description:
The primary focus of the Sneddon laboratory is pancreatic development and type 1 diabetes, and we employ the tools of stem cell biology, developmental biology, genomics, and tissue engineering. The candidate will be expected to contribute to ongoing work in these areas, with specific duties including human embryonic stem cell culture, mouse husbandry and transplantations, FACS analysis, and genomics techniques. The position represents an opportunity to be at the cutting edge of translational research in a highly collaborative scientific environment.
Additionally, the specialist will be expected to assist with managing day-today lab operations, perform general lab duties, and act as a supportive and positive lab citizen.
A 2-year commitment is preferred. Depending on performance and workload, opportunities for independent research, mentorship of other trainees, and scientific writing will be available.
Required Qualifications:
- Must have (or be in process of obtaining) a bachelor’s degree (or equivalent degree) or four years of research experience to be appointed at the Junior rank.
- Must have (or be in process of obtaining) a master’s degree (or equivalent degree) or a bachelor’s degree (or equivalent degree) with three or more years of research experience to be appointed at the Assistant rank.
- Must have (or be in process of obtaining) a master’s degree (or equivalent degree) or at least five to ten years of research experience to be appointed at the Associate rank.
- Must have (or be in process of obtaining) a terminal degree (or equivalent degree) or at least ten or more years of research experience to be appointed at the Full rank.
- Excellent organizational and interpersonal communication skills (verbal and written).
- Willingness and ability to learn new methods and skills for changing research priorities.
- Ability to work independently and as a member of a research team.
- Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
Preferred Qualifications:
- Prior experience with culturing human embryonic stem cells.
- Prior experience with mouse handling.
- Prior experience with bioinformatics analysis, such as single-cell RNA-sequencing data.
See Table 24B for the salary range for this position. A reasonable estimate for this position is $53,100-$188,200.
Please apply online at https://aprecruit.ucsf.edu/JPF05502 with cover letter, CV, and contact information for three references. Applicant materials must list current and/or pending qualifications upon submission. The selected candidate must meet all of the qualifications at the time of appointment.
Junior/Assistant Specialist - Nowakowski Lab
The Nowakowski Lab at UCSF is seeking a highly motivated scientist to join our dynamic research team. The successful candidate will be responsible for designing, conducting, and analyzing experiments related to stem cell biology, with a focus on understanding cellular differentiation and disease modeling using brain organoids. This position offers an exciting opportunity to contribute to cutting-edge research and therapeutic development in a collaborative and innovative environment. Ideal candidates will be able to thrive in a highly dynamic, collaborative, and multi-disciplinary environment. Applications from candidates with hands-on experience with stem cell culture, differentiation, and characterization techniques, proficiency in molecular biology techniques, including PCR, Western blotting, immunofluorescence, and flow cytometry, familiarity with gene editing tools (e.g., CRISPR/Cas9) and their application in stem cell research are strongly encouraged. We encourage applicants from all backgrounds and strive to maintain an inclusive research environment. Excellent problem-solving abilities and a creative approach to experimental design, strong communication skills, both written and verbal, with the ability to work collaboratively in a team environment, as well as commitment to maintaining a safe and ethical laboratory environment are essential. Applicants appointed at the Junior rank must possess a Baccalaureate degree (or equivalent degree) or at least four years of research experience, by the time of hire. Applicants appointed at the Assistant rank must possess a Master’s degree or a baccalaureate degree with 3 or more years of research experience, by the time of hire. Applicants’ materials must list current and/or pending qualifications upon submission.
Key Responsibilities:
- Design and execute experiments involving the culture, differentiation, and characterization of various stem cell types, including embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), and adult stem cells.
- Develop and optimize protocols for the differentiation of stem cells into specific cell types of interest.
- Perform high-throughput screening and gene editing (e.g., CRISPR/Cas9) to investigate gene function and regulatory networks in stem cell biology.
- Collaborate with cross-functional teams to integrate stem cell research with other disciplines, such as genomics, bioinformatics, and drug discovery.
- Analyze and interpret experimental data using statistical and bioinformatic tools.
- Prepare and present research findings in internal meetings, conferences, and peer-reviewed publications.
- Contribute to the writing of grant proposals and reports to secure funding for research projects.
- Maintain detailed and accurate records of all experiments and protocols.
- Stay current with the latest advancements in stem cell research and related fields.
See Table 24B for the salary range for this position. A reasonable estimate for this position is $53,100 - $68,300.
Please apply online at https://aprecruit.ucsf.edu/JPF05251.
Junior/Assistant Specialist - Nowakowski Lab
The Nowakowski lab is looking for motivated individuals to join the team at the UCSF Mission Bay campus. As a research scientist, you will join a rapidly evolving team to develop tools and technologies for studying brain development for the NIH-funded BRAIN Initiative and Chan-Zuckerberg Human Cell Atlas projects, among others. Your responsibilities will include but will not be limited to designing, developing, and optimizing molecular tools for studying development of the cerebral cortex, and scalable molecular tools for studying psychiatric disease candidate mutations on brain development. You will be training people how to use equipment and deploy technologies across projects within the laboratory, and across the collaborating groups.
Required Qualifications:
- Specialists appointed at the junior rank must possess (or in process of obtaining) a baccalaureate degree (or equivalent degree) or at least four years of research experience (e.g., with instrumentation and research equipment, social science research methods, or creative activities).
- Specialists appointed at the Assistant rank must possess (or in process of obtaining) a Master’s degree (or equivalent degree) or a baccalaureate degree with 3 or more years of research experience.
- Applicants must have obtained the degree requirement for the Specialist rank by the time of hire.
- Applicants’ materials must list current and/or pending qualifications upon submission.
- Excellent interpersonal, collaborative, and communication skills are expected, as well as attention to details and high organizational, documentation and time management skills.
- We are looking for candidates who can work independently and are self-motivated but are also able to excel in a highly collaborative environment.
Preferred Qualifications:
- Prefer degree in Biochemistry, Molecular Biology, Neuroscience, or a related field.
- At least one year of working with a cellular, tissue or animal model of brain such as brain organoids is highly encouraged.
- Expertise in molecular biology, cloning, and viral tool design is encouraged.
- Experience in fluorescence microscopy (such as confocal), in situ hybridization, sequencing library construction are highly encouraged.
- Some experience in Next-Gen Sequencing and bioinformatics is encouraged.
See Table 24B for the salary range for this position. A reasonable estimate for this position is $51,300 - $65,900.
Please apply online at https://aprecruit.ucsf.edu/JPF05116.
Junior/Assistant/Associate/Full Specialist - Nystul Lab
The Nystul lab is seeking a Junior/Assistant/Associate/Full Specialist to join our group and contribute to new and ongoing projects. Our lab focuses on epithelial stem cells using Drosophila melanogaster as a model. The successful applicant will design and perform experiments to investigate mechanisms of competition for an epithelial stem cell niche using the Drosophila as a model. The applicant will develop a detailed understanding of Drosophila genetics, Drosophila oogenesis, stem cell biology, and epithelial biology. An exceptional candidate will lead their own independent project, develop new ideas, be familiar with the literature, and participate in procurement of funds, where appropriate. Additionally, the specialist will be expected to assist with managing day-to-day lab operations, and perform general lab duties and be a positive lab citizen.
Required Qualifications:
- Excellent organizational and interpersonal communication skills (verbal and written)
- Willingness and ability to learn new methods and skills for changing research priorities.
- Ability to work independently and as a member of a research team.
- Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
- Must have (or be in process of obtaining) a baccalaureate degree (or equivalent degree) or four years of research experience to be appointed at the Junior rank.
- Must have (or be in process of obtaining) a master’s degree (or equivalent degree) or a baccalaureate degree with three or more years of research experience to be appointed at the Assistant rank.
- Must have (or be in process of obtaining) a master’s degree (or equivalent degree) or at least five to ten years of research experience to be appointed at the Associate rank.
- Must have (or be in process of obtaining) a terminal degree (or equivalent degree) or at least ten or more years of research experience to be appointed at the Full rank.
Preferred Qualifications:
- Experience with laboratory research using Drosophila as an experimental model
- Experience with whole-mount tissue immunofluorescence
- Knowledge of the developmental properties of cells and tissues
- Experience with identifying and reviewing relevant scientific literature
- Experience with developing and writing wet-lab protocols
- Knowledge about research design, ethics in research, and data presentation
We are seeking at least a 1-year commitment. Depending on performance and workload, opportunities for independent research, mentorship of other trainees, and scientific writing will be available.
Applicants must meet requirements by the time of appointment.
Please apply online at https://aprecruit.ucsf.edu/JPF04928.
Junior Specialist - Padmanabahn Lab
The Padmanabhan Lab is now recruiting a Junior Specialist. The areas of specialization and responsibilities for this position include:
• Culture and genetically manipulate mouse embryonic stem (mES) and human induced pluripotent stem (hIPS) cells and perform directed differentiation to atrial and ventricular cardiomyocytes.
• Design, generate, and validate novel genotyping protocols for engineered mouse genetic alleles and cell lines.
• Assessment gene expression by quantitative PCR.
• Perform timed matings and dam dissections to isolate mouse embryos at various stages of development.
• Perform rapid DNA isolation and genotyping of mouse embryos immediately following sample collection.
• Process embryonic and adult tissues for histologic evaluation.
• Perform standard molecular biology and biochemistry techniques (including molecular cloning, virus preparation and in vitro/in vivo viral transduction, Western blotting, immunoprecipitation, co-immunoprecipitation, and chromatin immunoprecipitation).
• Organize and actively maintain a mouse colony of 80-100 cages.
• Collaborate with other laboratory staff to rapidly complete necessary tasks and move research program forward.
• Maintain a pristine laboratory notebook and organize all collected data and samples appropriately.
• Perform basic statistical analysis, organize collected data into a presentable format, and summarize findings in narrative form.
Required qualifications:
• Bachelor’s Degree in Biological Sciences, Bioengineering, or related fields.
• At least 1-year of experience working in a research laboratory in either academia or industry settings.
• Knowledge of cell culture, standard molecular biology and biochemistry techniques, and in vivo mouse modeling.
• Demonstrated ability to contribute data to ongoing research efforts.
• Skill in independently resolving broad problems that may arise in collection or analysis of laboratory data.
• Self-motivated with ability to work independently and as part of a team.
• Able to learn effectively and meet deadlines.
• Demonstrated effective communication and interpersonal skills.
• Proven ability to successfully work on multiple concurrent projects.
• Ability to effectively manage their time.
• Proven ability to understand research cycles and rapidly perform experiments necessary for manuscripts in revision.
• Interest and proven ability to work closely with other members of the team towards carrying out the broader goals of the laboratory.
Appointees in the Specialist series will be expected to engage in specialized research, professional activities and do not have teaching responsibilities. Specialists are expected to use their professional expertise to make scientific and scholarly contributions, and may participate in University and Public Service. Screening of applicants will begin immediately and will continue as needed throughout the recruitment period. Salary will be commensurate with the applicants experience and training.
Please apply online at https://aprecruit.ucsf.edu/JPF04804. Applicants’ materials must list current and/or pending qualifications upon submission.
Genetics
Research Associate I - Conklin Lab
The Conklin Lab is part of Gladstone’s pioneering efforts in human therapeutic genome editing, with a strong focus on DNA repair mechanisms. Working in close partnership with the Innovative Genomics Institute, our lab applies advanced molecular biology techniques and cellular models to explore new strategies for correcting genetic defects. For more information, visit www.conklinlab.org.
We are seeking a Research Associate I to support ongoing projects focused on DNA repair and genome editing, particularly using motor neurons as a model system. This role offers a unique opportunity to work at the forefront of molecular and cellular biology and contribute to high-impact translational research.
What you will do:
- Conduct experiments to study the basic mechanisms of DNA repair.
- Perform DNA excision assays and related molecular techniques in cell culture systems.
- Utilize motor neurons derived from stem cells as a disease-relevant model.
- Maintain and differentiate human cell lines, including iPSC-derived neurons.
- Analyze and document experimental data; assist with interpretation and presentation.
- Collaborate with team members across projects and contribute to lab meetings and discussions.
- Ensure compliance with lab protocols, safety standards, and institutional guidelines.
What you will need:
- Bachelor’s degree (BA/BS) in Biology, Molecular Biology, Genetics, or a related discipline (preferred).
- Prior experience working in a biological research laboratory (required).
- Familiarity with molecular biology techniques, such as PCR, DNA/RNA extraction, gel electrophoresis, and cloning (preferred).
- Experience with cell culture, especially human or stem cell-derived lines (preferred).
- Excellent written and verbal communication skills.
- Detail-oriented, highly organized, and capable of working independently or in a team environment.
- Strong interest in genome editing and human disease modeling.
*Individuals intending to pursue graduate studies in biomedical sciences are strongly encouraged to apply.
Hiring Range:
$27-$31hr
Apply at: https://gladstone.wd5.myworkdayjobs.com/en-US/careers/job/Research-Associate-I--Conklin-Lab_REQ-3155
Junior/Assistant/Associate/Full Specialist - Singh Lab
SCHOOL OF MEDICINE – Department of Anatomy
Description
The Singh Lab at UCSF (www.singhlabucsf.org) is seeking a highly motivated Junior/Assistant/Associate/Full Specialist to join our research program at the intersection of aging biology, genomics, and machine learning. Our lab is tackling the fundamental questions in the field of aging using a multi-disciplinary approach. We integrate cutting-edge single-cell RNA sequencing (scRNA-seq) and other multi-omics datasets with advanced machine learning techniques to decipher the intricate genomic changes that drive aging and age-related diseases. We not only work with human and mouse data – we're also exploring the remarkable biology of the African killifish, a powerful model organism for aging research. By comparing genomic patterns across species, we aim to identify conserved processes that underlie aging and develop innovative strategies to promote healthy lifespan.
As a Junior/Assistant/Associate/Full Specialist in our lab, you will:
- Spearhead the development and application of novel AI/ML algorithms to analyze large-scale scRNA-seq datasets related to aging.
- Uncover hidden patterns and predict age-related changes and 'aging clocks' at the single-cell level.
- Identify key genes, pathways, and cell types that contribute to aging and age-related diseases.
- Collaborate with a dynamic team of researchers with multi-disciplinary expertise in genomics, bioinformatics, and aging biology.
- Contribute to a vibrant research community at UCSF, including the Bakar Aging Research Institute (BARI) and the Bakar Computational Health Sciences Institute (BCHSI).
Required qualifications:
- Must have (or be in process of obtaining) a bachelor’s degree (or equivalent degree) or four years of research experience to be appointed at the Junior rank.
- Must have (or be in process of obtaining) a master’s degree (or equivalent degree) or a bachelor's degree with three or more years of research experience to be appointed at the Assistant rank.
- Must have (or be in process of obtaining) a master's degree (or equivalent degree) five to ten years of research experience to be appointed at the Associate rank.
- Must have (or be in process of obtaining) a terminal degree (or equivalent degree) or at least ten or more years of research experience to be appointed at the Full rank.
Preferred Qualification:
- Proven experience analyzing scRNA-seq, scATAC-seq or spatial-RNA-seq data.
- Proven experience expertise in AI/ML applied to genomic data.
- Proficiency in Python and relevant libraries for machine learning (e.g., scikit-learn, TensorFlow, PyTorch).
We will consider applications on a rolling basis until all positions are filled. We are seeking at least a 2-year commitment. Applicants must meet requirements by the time of the appointment.
Please apply online at https://aprecruit.ucsf.edu/JPF05498
See Table 24B for the salary range for this position. A reasonable estimate for this position is $53,100-$188,200.
Research Specialist - Sangokoya Lab
The Sangokoya Lab at the University of California, San Francisco (UCSF) Parnassus campus has an opening for a research specialist. The lab is centered on 1) the investigation of two-dimensional and three-dimensional mammalian stem cell models (basic stem cell biology) and 2) human liver pathobiology (liver pathology, cell-based tissue culture models). Both areas focus on the biological effects of RNA-based regulation on development, biology, and disease both in-vitro and in-vivo models as well as human tissue.
A research specialist in the Sangokoya Lab will be a key laboratory member assisting with management of daily operations of the lab, assisting with ongoing experiments, and acting as an interfacing point of contact for lab activities and maintenance as necessary. The ideal candidate will have a high level of organization and be a strong communicator, ensuring compliance with all regulatory requirements, including maintaining laboratory spaces and equipment. Additionally, the candidate will have the opportunity to contribute, learn, and utilize a variety of research techniques as aligned with previous experience, skills, and expertise.
All specialist responsibilities include but are not limited to:
- Administrative lab duties including; lab schedules, staff onboarding, and ensuring compliance with safety guidelines.
- Manage daily lab operations including; organizing the lab space, maintaining a sterile and well-stocked lab environment, inventory, ensuring equipment and maintenance.
- Assist with research projects, with the capability to work independently.
- Have and maintain up-to-date general knowledge of molecular biology techniques as necessary to complete tasks and projects.
- If background is wet-lab-based, should have or be amenable to acquiring basic computational biology (analysis) skills including analysis of sequencing datasets (RNA-seq, single-cell RNA-seq, spatial analysis), image-based analysis (i.e. Imaris, ImageJ, FIJI-based programs). Other knowledge areas (protein-based, chemical biology, engineering) considered as related to current opportunities in lab.
- Additional responsibilities may include: performing molecular biology techniques including RNA/DNA extraction, PCR, basic protein preparations/analysis (i.e. western blot) plasmid preparation and basic cloning, performing imaging/cytometry techniques including immunofluorescence, immunohistochemistry, flow cytometry, performing basic data analysis, scientific writing, mouse work including handling/imaging/dissection. Prior experience in these areas are highly valued, but comparable expertise and skills in relevant scientific areas not listed will be considered.
The specialist will be expected to work well as part of a team, yet be able to work independently with high regard for rigorous standards. The specialist will have enthusiasm for the practice of science, and be a positive lab citizen. This position is ideal for a candidate with a background in laboratory-based biology or complementary scientific backgrounds including molecular biology, bioengineering, biochemistry, and chemical biology.
Required Qualifications:
- Specialists appointed at the junior rank must possess a Baccalaureate degree (or equivalent degree) or at least four years of research experience.
- Specialists appointed at the Assistant rank must possess a Master’s degree or a baccalaureate degree with 3 or more years of research experience.
- Specialists appointed at the Associate rank must possess a Master’s degree (or equivalent degree) or five to ten years of experience in the relevant specialization.
- Specialists appointed at the full rank must possess a terminal degree (or equivalent degree) or ten or more years of experience in the relevant specialization.
- Excellent organizational and analytical skills.
- Excellent interpersonal communication (verbal and written).
- Ability to work independently, prioritize and coordinate tasks, and meet multiple deadlines.
- Applicant must have all requirements met by time of hire.
- Applicants’ materials must list current and/or pending qualifications upon submission.
Preferred Qualifications:
- Prior laboratory-based research experience.
- Prior experience with data analysis and/or image analysis, molecular biology and biochemistry techniques, cell culture ----are considered a plus.
- If background is wet-lab-based, the specialist should have or be amenable to acquiring basic computational biology (analysis) skills including analysis of sequencing datasets (RNA-seq, single-cell RNA-seq, spatial analysis), image-based analysis (i.e. Imaris, ImageJ, FIJI-based programs). Other knowledge areas (protein-based, chemical biology, engineering) considered as related to current opportunities in lab.
- Experience in microscopy, imaging; confocal or other advanced microscopy preferred.
- Experience in programming/coding-based analysis of datasets using R-based (or other programming language) programs.
- Scientific curiosity and a strong motivation to contribute to the field.
See Table 24B for the salary range for this position. A reasonable estimate for this position is $53,100 - $188,200.
Please apply online at https://aprecruit.ucsf.edu/JPF05414.
Microbiology and Immunology
Junior/Assistant/Associate/Full Specialist - Mukherjee Lab
The candidate will be responsible for laboratory research duties as well as lab management duties. This position will involve experiments including bacterial culture, mammalian cell culture, macrophage infections, microscopy, molecular biology, gene expression analysis, mammalian cell transfections, immunoprecipitations, protein gels, Western blotting; and perform other duties such as lab ordering/organization. The specialist will perform experiments with the bacterial pathogen Legionella pneumophila. General lab managerial tasks such as cataloging and ordering reagents are part of the position, and other duties as assigned. In addition independent research projects are available separate from the above describe duties. The Mukherjee lab is a highly collaborative space that is pushing the cutting edge of host-pathogen biology. Additionally, the specialist will be expected to assist with managing day-to-day lab operations, and perform general lab duties and be a positive lab citizen.
Required Qualifications:
• Excellent organizational and interpersonal communication skills (verbal and written).
• Willingness and ability to learn new methods and skills for changing research priorities.
• Ability to work independently and as a member of a research team.
• Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
• Must have (or be in process of obtaining) a baccalaureate degree (or equivalent degree) or four years of research experience to be appointed at the Junior rank.
• Must have (or be in process of obtaining) a master’s degree (or equivalent degree) or a a baccalaureate degree with three or more years of research experience to be appointed at the Assistant rank.
• Must have (or be in process of obtaining) a master’s degree (or equivalent degree) or at least five to ten years of research experience to be appointed at the Associate rank.
• Must have (or be in process of obtaining) a terminal degree (or equivalent degree) or at least ten or more years of research experience to be appointed at the Full rank.
Preferred Qualifications:
• Prior experience with handling pathogenic microbes, aseptic techniques
• Prior experience in the design and assembly of DNA constructs
We are seeking at least a 2-year commitment. Depending on performance and workload, opportunities for independent research, mentorship of other trainees, and scientific writing will be available.
Applicants must meet requirements by the time of appointment.
Please apply online at https://aprecruit.ucsf.edu/JPF05174. Applicants’ materials must list current and/or pending qualifications upon submission.
Junior or Assistant Specialist-Ricardo-Gonzalez Lab
The Ricardo-Gonzalez Lab (rrglab.com) is a recently established immunology laboratory interested in understanding how tissue-resident immune cells influence tissue physiology and function. The research specialist will perform basic and translational research to investigate the role of innate and adaptive immune cells in tissue homeostasis and models of infection, inflammation, and cancer. We seek a specialist who will assist the team by performing laboratory and investigative procedures using a wide array of experimental techniques such as flow cytometry, immunofluorescence imaging, PCR, cell culture (cell lines and primary cells), plasmid prep and purification, molecular cloning, and ELISA-like assays. Translational research components will involve experiments with human blood and tissue samples. Specialist responsibilities regarding mouse model systems will include breeding, screening, and immunizing mice as well as dissecting tissues to obtain cells for culture and analysis of gene expression.
Required Qualifications:
- Excellent organizational skills
- Willingness and ability to learn new methods and skills as needed for changing research priorities.
- Ability to work independently and as a member of a research team.
- Must be organized and have the ability to prioritize tasks, coordinate work tasks with others, and manage to meet multiple deadlines.
- Ability to maintain a comprehensive laboratory notebook of experiments done on a daily basis.
- Demonstration of accuracy and attention to detail in sample preparation during prior research experience is required.
- Excellent interpersonal communication, ability to consent and recruit patients for the studies.
- Ability to use or learn to enter information into REDCap database.
- Specialist appointed at the Junior rank must possess (or be in process of obtaining) a bachelor’s degree (or equivalent degree) in biology, biochemistry, or a related scientific discipline or four years of research experience.
- Specialists appointed at the Assistant rank must possess (or be in process of obtaining) a master’s degree (or equivalent degree) in biology, biochemistry, or a related scientific discipline or a bachelor’s degree in biology, biochemistry, or a related scientific discipline with three or more years of research experience.
- Candidates must meet the requirements by the time of appointment.
Preferred Qualifications:
- Experience with mouse models of human disease
- Experience with cell culture and sterile technique
- Experience with infectious disease models in mice
- Computational biology coursework and/or research experience
- Flow Cytometry (FACS): Ability to perform multicolor flow cytometry.
- Transgenic Mouse Work: Experience with experimental animal research. Comfort with handling, manipulating, euthanizing, and dissecting experimental animals.
- Fluorescence Microscopy: Experience with sample preparation, immunofluorescence staining, and use of epifluorescence and confocal microscopes for image acquisition.
- Communication, logistical, and time management skills to coordinate work with other lab members.
Licensure/Certification/Registration: None required.
Physical Requirements:
- Good visual acuity and accurate color discrimination.
- The position requires excellent manual dexterity and familiarity utilizing delicate instrumentation.
- Occasionally lifts and/or carries objects weighing up to 20 pounds.
- Work involves possible exposure to malodorous vapors, low dose radiation, contamination by toxic chemicals and acids and presence of carcinogenic substances.
- Long periods of standing and/or sitting.
Please apply online at https://aprecruit.ucsf.edu/JPF04888, and submit a CV, cover letter and 3 reference contacts.
Junior/Assistant/Associate/Full Specialist - Wilson Lab
The Wilson Lab is seeking a Junior, Assistant, Associate, or Full Specialist. The Specialist will be responsible for laboratory management duties, perform cell culture techniques, molecular microbiology, microscopy and data analysis, develop new in vitro and in vivo models for bacterial, fungal and cancer imaging, and working collaboratively on a range of exciting projects.
Required Qualifications:
- Specialists appointed at the Junior rank must possess a baccalaureate degree in Microbiology or in a related science (or equivalent degree) or at least four years of research experience.
- Specialists appointed at the Assistant rank must possess a master’s degree (or equivalent degree) or a baccalaureate degree with three or more years of research experience.
- Specialists appointed at the Associate rank must possess a master’s degree (or equivalent degree) or five to ten years of research experience.
- Specialists appointed at the Full rank must possess a terminal degree (or equivalent degree) or ten or more years of research experience.
- Applicants must meet all the qualifications by the time of hire.
- Applicant materials must list current and/or pending qualifications upon submission.
Preferred Qualifications:
- At least 2 years of postdoctoral experience in animal studies and PET imaging.
- Experience with MRI, radiolabeling, antibodies.
- Cell culture and microscopy skills.
See Table 24B for the salary range for this position. A reasonable estimate for this position is $53,100-$188,200.
Please apply online at https://aprecruit.ucsf.edu/JPF05416 with a cover letter, CV, and contact information for three references.
Junior Research Specialist - Nayak Lab
The Nayak Lab (nayak.ucsf.edu) has an opening for a junior research specialist who is interested in advancing our knowledge of the gut microbiome and its impact on rheumatic diseases, such as rheumatoid arthritis. We use multiple state-of-the-art technologies, including bacterial genomics, metabolomics, anaerobic microbiology, bacterial genetics, gnotobiotic animal models, and studies of patient cohorts to elucidate the mechanisms by which gut microbiota impact patient response to treatment of rheumatic disease. A major driving force of the lab is the advancement of precision medicine for patients with rheumatic disease.
The candidate will contribute to new and ongoing projects in the lab. The candidate will use or learn a variety of techniques in anaerobic microbiology, microbial genomics, analytical chemistry, molecular biology, cell culture, mouse work, computational analysis, and immunology. Additionally, the specialist will be expected to assist with managing day-to-day lab operations, perform general lab duties, and be a positive lab citizen. Candidates will be expected to work independently and be active contributors to the collaborative multidisciplinary team of microbiologists, immunologists, and computational biologists. The successful candidate will report directly to Dr. Renuka Nayak, MD, PhD but will work closely with collaborators within and outside of the group. An exceptional candidate will lead their own independent project, develop new ideas, be familiar with the literature, and participate in procurement of funds, where appropriate. Candidates interested in pursuing MD, PhD, or MD/PhD. training will benefit most from this laboratory experience.
Required Qualifications:
• Excellent organizational and interpersonal communication skills (verbal and written).
• Willingness and ability to learn new methods and skills for changing research priorities.
• Ability to work independently and as a member of a research team.
• Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
• Familiarity with standard wet lab techniques (e.g. preparation of reagents/chemicals, basic microbiology, tissue culture, PCR, western blot, DNA/RNA purification) and/or computational analysis of large datasets.
• Must have (or be in process of obtaining) a bachelor’s degree (or equivalent degree) or at least four years of research experience.
Preferred Qualifications:
• Prior experience with handling pathogenic microbes, aseptic techniques
• Prior experience in high throughput sequencing and analysis
• Prior experience in mass spectrometry or other analytical chemistry approaches
• Prior experience in flow cytometry or other immune profiling methods
• Prior experience in the design and assembly of DNA constructs
• Prior experience in bacterial genome manipulation
• Prior experience working with mice
We are seeking at least a 2-year commitment. Depending on performance and workload, opportunities for independent research, mentorship of other trainees, and scientific writing will be available. Applicants must meet requirements by the time of appointment.
The Nayak Lab is located at the San Francisco VA Medical Center, perched atop Land’s End and overlooking the San Francisco Bay. We are a part of the University of California, San Francisco (UCSF) Benioff Center for Microbiome Medicine (BCMM), enabling engagement with a rich community of investigators and access to cutting-edge resources for promoting microbiome research.
Please apply online at https://aprecruit.ucsf.edu/JPF05470. Applicants’ materials must list current and/or pending qualifications upon submission.
See Table 24B for the salary range for this position. A reasonable estimate for this position is $53,100-$56,600.
Junior/Assistant/Associate/Full Specialist - Kamber Lab
The Kamber lab (www.kamberlab.com) is seeking a Junior/Assistant/Associate/Full Specialist to join our group and contribute to new and ongoing projects. Our lab focuses on the discovery of novel molecules that govern the ability of our immune system to recognize and destroy cancer cells and which may serve as new therapeutic targets for currently untreatable cancers. In particular, we are interested in identifying genes and proteins that regulate macrophage-mediated clearance of cancer cells. We are also interested in developing innovative CRISPR-based screening approaches to enable exploration of a wider range of understudied macrophage-related phenomena. The candidate will be expected to contribute to the core research efforts in the lab, by conducting molecular and cell biological techniques, including molecular cloning, tissue culture, CRISPR-mediated gene editing, automated live-cell imaging, flow cytometry, and next-generation sequencing. An exceptional candidate will design their own experiments, lead their own independent project, develop new ideas, be familiar with the literature, present at lab meetings, and participate in procurement of funds, where appropriate. Additionally, the specialist will be expected to assist with managing day-to-day lab operations, and perform general lab duties and be a positive lab citizen.
Required Qualifications:
- Excellent organizational and interpersonal communication skills (verbal and written)
- Willingness and ability to learn new methods and skills for changing research priorities.
- Ability to work independently and as a member of a research team.
- Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
- Must have (or be in process of obtaining) a bachelor’s degree (or equivalent degree) or four years of research experience to be appointed at the Junior rank.
- Must have (or be in process of obtaining) a master’s degree (or equivalent degree) or a bachelor’s degree with three or more years of research experience to be appointed at the Assistant rank.
- Must have (or be in process of obtaining) a master’s degree (or equivalent degree) or five to ten years of research experience to be appointed at the Associate rank.
- Must have (or be in process of obtaining) a terminal degree (or equivalent degree) or at least ten or more years of research experience to be appointed at the Full rank.
Preferred Qualifications:
- Prior experience in the design and assembly of DNA constructs
- Prior experience in mammalian cell culture and genome manipulation (i.e. gene knockouts) and high throughput sequencing
We are seeking at least a 1-year commitment. Depending on performance and workload, opportunities for independent research, mentorship of other trainees, and scientific writing will be available. This position offers the opportunity for close mentorship in a supportive and friendly environment, as well as guidance and support in achieving their long-term career goals (including training in oral and written communication, flexible scheduling to accommodate preparation for graduate/medical school examinations and interviews, and opportunities for networking with other scientists).
Applicants are strongly encouraged to submit a cover letter with their application, describing their past research experiences, research interests, career goals, and the length of time they intend to commit to the position (e.g. 1 years, 2 years, or more).
Applicants must meet requirements by the time of appointment.
Please apply online at https://aprecruit.ucsf.edu/JPF05182
See Table 24B for the salary range for this position. A reasonable estimate for this position is $53,100-$188,200.
Junior Specialist – Krummel Lab
Involves a hybrid of computational, data analytics, and systems immunology specialization with emphasis of the former two. Working at the junction of the three of these to learn basic principles of the immune system. Incumbent will apply computational, computer science, data science to perform research and to drive hypotheses for subsequent analysis in the lab. Responsibilities include research, design, development, analysis, operation, and support of data science research, software, tools and hardware resources. The incumbent will work closely with immunologists to develop data algorithms and perform computation, statistical analyses, and interpretation and reporting of research. Works and can listen and talk to biologists as well as those with various computational expertise.
Required Qualifications:
- Specialists appointed at the junior rank must possess a baccalaureate degree (or equivalent degree) or at least four years of relevant research experience by the time of hire.
- Applicants’ materials must list current and/or pending qualifications upon submission.
- Intermediate knowledge of data science tools including facility with Python and R.
- Proven skills and experience in independently resolving broad computing / data science problems using introductory and / or intermediate principles.
Preferred Qualifications:
- Demonstrated broad experience in one or more of the following: matrix factorization methods and knowledge networks.
Appointees in the Specialist series will be expected to engage in specialized research, professional activities and do not have teaching responsibilities. Specialists are expected to use their professional expertise to make scientific and scholarly contributions, and may participate in University and Public Service. Screening of applicants will begin immediately and will continue as needed throughout the recruitment period. Salary and rank will be commensurate with the applicants experience and training.
See Table 24B for the salary range for this position. A reasonable estimate for this position is $51,300 - $54,600.
Please apply online at https://aprecruit.ucsf.edu/JPF04990.
Junior or Assistant Research Specialist - Fassett Lab
The Fassett laboratory at the UCSF-Parnassus Campus is looking for a dedicated and enthusiastic recent college graduate to join our team as a junior/asst research specialist. Founded in spring 2023, our growing research group studies T cell biology and allergic inflammation in skin, lungs, and gut. Your direct supervisor will be Dr. Marlys Fassett, a physician-scientist/dermatologist whose research program spans from in vitro molecular immunology to neuroimmunology to mouse models of inflammatory disease.
Required: The ideal candidate will have completed relevant coursework in neuroscience, immunology or molecular biology
Preferred: hands-on research experience in immunology
Key experimental techniques you will be expected to learn and perform with us include: mouse and human tissue processing, flow cytometry, mouse husbandry, and other animal procedures. Up to 10% of your time will also be dedicated to general lab support such as ordering and receiving of supplies. We also intend to support you as you develop sufficient skills and autonomy to drive an independent research sub-project within the lab. Depending upon your prior experience and interest, your project may involve experiments that employ immunofluorescence microscopy, analysis of RNA-sequencing data, or development of novel assays to model the relationship between sensory nerves and other skin cell types in vitro.
The Position: Appointees in the Specialist series will be expected to engage in specialized research, professional activities and do not have teaching responsibilities. Specialists are expected to use their professional expertise to make scientific and scholarly contributions and may participate in University and Public Service. Specialists appointed at the junior rank must possess a baccalaureate degree (or equivalent degree) or equivalent research experience (e.g., with instrumentation and research equipment, social science research methods, or creative activities). Specialists appointed at the Assistant rank must possess a master’s degree (or equivalent degree) or a bachelor’s degree with three or more years of research experience. Preference given to candidates with hands on experience in flow cytometry, in vitro cell differentiation assays, and/or other core immunology techniques. Candidates must meet all of the required qualifications at the time of appointment. Candidate’s CV must state qualifications (or if pending) upon submission.
Timing: Screening of applicants will begin immediately and will continue as needed throughout the recruitment period. Salary and rank will be commensurate with the applicants experience and training. The anticipated start date on is on or before [date].
Contact: To be considered for the position you must also apply online at https://aprecruit.ucsf.edu/JPF04896, with a CV and the contact information of three references.
Junior or Assistant Specialist - Ricardo-Gonzalez Lab
Department of Dermatology
Job Description
The Ricardo-Gonzalez Lab (rrglab.com) is a recently established immunology laboratory interested in understanding how tissue-resident immune cells influence tissue physiology and function. The research specialist will perform basic and translational research to investigate the role of innate and adaptive immune cells in tissue homeostasis and models of infection, inflammation, and cancer. We seek a specialist who will assist the team by performing laboratory and investigative procedures using a wide array of experimental techniques such as flow cytometry, immunofluorescence imaging, PCR, cell culture (cell lines and primary cells), plasmid prep and purification, molecular cloning, and ELISA-like assays. Translational research components will involve experiments with human blood and tissue samples. Specialist responsibilities regarding mouse model systems will include breeding, screening, and immunizing mice as well as dissecting tissues to obtain cells for culture and analysis of gene expression.
Required Qualifications:
- Excellent organizational skills
- Willingness and ability to learn new methods and skills as needed for changing research priorities.
- Ability to work independently and as a member of a research team.
- Must be organized and have the ability to prioritize tasks, coordinate work tasks with others, and manage to meet multiple deadlines.
- Ability to maintain a comprehensive laboratory notebook of experiments done on a daily basis.
- Demonstration of accuracy and attention to detail in sample preparation during prior research experience is required.
- Excellent interpersonal communication, ability to consent and recruit patients for the studies.
- Ability to use or learn to enter information into REDCap database.
- Specialist appointed at the Junior rank must possess (or be in process of obtaining) a bachelor’s degree (or equivalent degree) in biology, biochemistry, or a related scientific discipline or four years of research experience.
- Specialists appointed at the Assistant rank must possess (or be in process of obtaining) a master’s degree (or equivalent degree) in biology, biochemistry, or a related scientific discipline or a bachelor’s degree in biology, biochemistry, or a related scientific discipline with three or more years of research experience.
- Candidates must meet the requirements by the time of appointment.
Preferred Qualifications:
- Experience with mouse models of human disease
- Experience with cell culture and sterile technique
- Experience with infectious disease models in mice
- Computational biology coursework and/or research experience
- Flow Cytometry (FACS): Ability to perform multicolor flow cytometry.
- Transgenic Mouse Work: Experience with experimental animal research. Comfort with handling, manipulating, euthanizing, and dissecting experimental animals.
- Fluorescence Microscopy: Experience with sample preparation, immunofluorescence staining, and use of epifluorescence and confocal microscopes for image acquisition.
- Communication, logistical, and time management skills to coordinate work with other lab members.
Licensure/Certification/Registration: None required.
Physical Requirements:
- Good visual acuity and accurate color discrimination.
- The position requires excellent manual dexterity and familiarity utilizing delicate instrumentation.
- Occasionally lifts and/or carries objects weighing up to 20 pounds.
- Work involves possible exposure to malodorous vapors, low dose radiation, contamination by toxic chemicals and acids and presence of carcinogenic substances.
- Long periods of standing and/or sitting.
Please apply online at https://aprecruit.ucsf.edu/JPF04888, and submit a CV, cover letter and 3 reference contacts.
See Table 24B for the salary range for this position. A reasonable estimate for this position is $51,300-$65,900.
Junior Specialist – Turnbaugh Lab
The Turnbaugh lab is seeking a Junior Specialist to join our group and contribute to new and ongoing projects. This work will focus on the study of the microbiome using Gnotobiotic mice, and will include performing advanced experimental techniques to execute experiments (for example, the Specialist may administer experimental agents via oral, i.p., or subcutaneous routes, and follow up with experimental disease scoring and tracking, dissection and processing of tissues, or other techniques deemed experimentally necessary). Lab techniques performed by the Specialist include (but are not limited to): DNA extraction, PCR, qPCR, microbial cultures, gram staining, and genotyping. The candidate will also be expected to contribute to novel projects advancing research and development of Gnotobiotic tools. For example, the candidate will work on the development of novel models (such as allergy and asthma) in sterile mice and the translation of embryo-transfer techniques into a germ-free setting, among other projects. An exceptional candidate will move these projects forward independently, helping the lab to develop and test new ideas. Additionally, the specialist will be expected to assist with managing day-to-day lab operations within the Gnotobiotic core facility, perform general lab duties, and be a positive lab citizen.
Required Qualifications:
• Excellent organizational and interpersonal communication skills (verbal and written)
• Willingness and ability to learn new methods and skills for changing research priorities.
• Ability to work independently and as a member of a research team.
• Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
• Must have (or be in process of obtaining) a bachelor’s degree (or equivalent degree) or at least four years of research experience to be appointed at the Junior rank.
Preferred Qualifications:
• Prior experience with handling pathogenic microbes, aseptic techniques
• Prior experience working in a research-based setting with murine models
• Prior experience in gnotobiotic mouse handling/maintenance in positive pressure isolators, with a focus on sterility
• Prior experience in advanced techniques in murine models (such as injection of compounds, oral gavage, anesthesia, surgery techniques and documentation)
We are seeking at least a 1-year commitment. Depending on performance and workload, opportunities for independent research, mentorship of other trainees, and scientific writing will be available.
Applicants must meet requirements by the time of appointment.
Please apply online at https://aprecruit.ucsf.edu/JPF04892
Infectious Diseases
Junior, Assistant, Associate, or Full Specialist - Turnbaugh Lab
The Turnbaugh lab is seeking a Junior/Assistant/Associate/Full Specialist to join our group and contribute to new and ongoing projects. Our lab studies the impact of the human gut microbiome on the treatment of both chronic and infectious diseases. We are also interested in discovering and engineering bacteriophage to manipulate microbiome composition and metabolic activity. The candidate will be expected to contribute to this tool development and microbiome research in the lab, by conducting microbiology and molecular biology techniques, including bacterial and bacteriophage manipulation, cloning, protein purification, sequencing, mass spectrometry, and biochemical assays. An exceptional candidate will lead their own independent project, develop new ideas, be familiar with the literature, and participate in procurement of funds, where appropriate. Additionally, the specialist will be expected to assist with managing day-to-day lab operations, and perform general lab duties and be a positive lab citizen.
Required qualifications:
• Junior Specialist - Baccalaureate degree (or equivalent degree) or at least four years of research experience.
• Assistant Specialist - Master’s degree or a baccalaureate degree with 3 or more years of research experience.
• Associate Specialist - Master’s degree (or equivalent degree) or five to ten years of experience in the relevant specialization.
• Full Specialist - terminal degree (or equivalent degree) or ten or more years of experience in the relevant specialization.
• Excellent organizational and interpersonal communication skills (verbal and written).
• Willingness and ability to learn new methods and skills for changing research priorities.
• Ability to work independently and as a member of a research team.
• Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
Preferred qualifications:
• Prior experience with handling pathogenic microbes, aseptic techniques.
• Prior experience in the design and assembly of DNA constructs.
• Prior experience in bacterial genome manipulation (i.e. gene knockouts, locus removal, introduction of chromosomal tags and point mutations).
• Prior experience in high throughput sequencing and analysis.
• Prior experience in mass spectrometry or other analytical chemistry approaches.
• Prior experience in flow cytometry or other immune profiling methods.
Please apply online at https://aprecruit.ucsf.edu/JPF05537. Applicants’ materials must list current and/or pending qualifications upon submission.
Staff Research Associate - Feeney Lab
Job Summary
The Feeney Lab, in the UCSF Division of Experimental Medicine, at Zuckerberg San Francisco General Hospital, is hiring a highly motivated SRA 1 or 2 to perform lab-based translational research, with general supervision, that aims to understand human immunity to childhood pathogens including malaria and CMV. The candidate will contribute to a research collaboration investigating childhood malaria in Uganda. Our lab strives to understand the human immune response to malaria and other childhood pathogens, and to harness this knowledge to improve vaccines, prevention strategies, and immunomodulatory therapies.
The incumbent will have responsibilities that include performance of cellular immunology assays based on flow cytometry (FACS ARIA and spectral flow cytometers), development and validation of new flow panels and assays, RNA expression analysis and sequencing, data management, as well as using programming languages to analyze high parameter cytometry and gene expression data. The candidate will also be expected to train new lab members in basic skills of PBMC separation and cryopreservation and basic immunology techniques. The research associate will help to apply these assays to hypothesis-driven research projects, working closely with postdoctoral fellows and graduate students while receiving additional direct mentorship from the PI. In addition, the SRA will perform basic lab management tasks including ordering of supplies, coordinating sample shipments to collaborators, attendance at safety meetings and enforcement of safety procedures, and coordination of laboratory inspections.
The purpose of this position is to perform cellular immunology assays on human blood samples from clinical research samples obtained in the malaria endemic region of Tororo, Uganda, The Staff Research Associate will be located in San Francisco, but will provide a role in helping to coordinate the activities of the PI’s field laboratory in Uganda with researchers in Uganda and San Francisco. As such, a successful candidate will possess exemplary communication skills and a capacity to work in a cross-cultural environment.
The final salary and offer components are subject to additional approvals based on UC policy.
Your placement within the salary range is dependent on a number of factors including your work experience and internal equity within this position classification at UCSF. For positions that are represented by a labor union, placement within the salary range will be guided by the rules in the collective bargaining agreement.
The salary range for this position is $28.04 - $45.09 (Hourly Rate).
To learn more about the benefits of working at UCSF, including total compensation, please visit: https://ucnet.universityofcalifornia.edu/compensation-and-benefits/index.html
Neurobiology
Staff Research Associate - Piao Lab
The Piao Lab at the University of California San Francisco (UCSF) is a vibrant, medium sized basic science laboratory studying neuroimmune signaling and its role in brain development, neuropsychiatric diseases, and neurodegeneration. We are part of the Department of Pediatrics and the Weill Institute for Neuroscience, in the brand-new Weill Neurosciences Building on the Mission Bay campus of UCSF. The lab currently has one research scientist, 6 postdoctoral fellows, one graduate student, and three technical staff performing experiments in mice, human cells, and brain organoids, with the long-term goal of discovering new immune based therapies for disorders including autism, schizophrenia, and neurodegenerative diseases like Alzheimer’s Disease.
This position is for a Lab Manager that will help to coordinate and oversee the research activities of the lab. The lab manager will be a key part of the lab, coordinating and communicating with lab personnel and serving as a liaison between the lab and the PI. This will include scheduling and calendaring of lab events, presentations, and retreats. The lab manager will also manage equipment maintenance and repairs, take primary responsibility for organizing reagents and laboratory samples, and perform other tasks needed to keep the lab running efficiently and effectively. As a staff scientist, they will also undertake research projects in collaboration with the supervisor and make innovative contributions, conduct independent research projects in the lab, such as analysis of immune cell populations in the brain by flow cytometry, histology, and other approaches in the setting of brain pathologies.
The ideal candidate will have excellent organizational, administrative, social, and communication skills, will be able to independently troubleshoot and problem-solve daily laboratory challenges, and will possess a genuine interest in biomedical science and science administration. The candidate should have substantial prior bench and research experience, including in general molecular biology, immunology, and brain tissue histology.
The final salary and offer components are subject to additional approvals based on UC policy.
Your placement within the salary range is dependent on a number of factors including your work experience and internal equity within this position classification at UCSF. For positions that are represented by a labor union, placement within the salary range will be guided by the rules in the collective bargaining agreement.
The salary range for this position is $30.89 - $49.68 (Hourly Rate).
To learn more about the benefits of working at UCSF, including total compensation, please visit: https://ucnet.universityofcalifornia.edu/compensation-and-benefits/index.html
Radiology
Junior/Assistant/Associate/Full Specialist - Sriram Lab
The Sriram Lab is seeking a Junior, Assistant, Associate, or Full Specialist. The specialist will be involved in development of hyperpolarized 13C MR markers using dissolution dynamic nuclear polarization (DNP) technology of tumor metabolism in the translational metabolic imaging laboratory of Dr. Renuka Sriram. (https://radiology.ucsf.edu/research/labs/translational-metabolic-imaging). The breadth of studies will encompass the chemical preparation of promising precursors and its testing in ex vivo models, validation in cutting edge preclinical models of urologic cancer. The studies will utilize living cells in bioreactors, patient derived tissue slices as well as mouse models. These biologically relevant animal models will be used to identify and validate imaging markers of disease presence, severity, and treatment response.
Another dimension of this project involves computational proficiency with data analysis kinetic modeling as well as multi-omics integration.
Required Qualifications:
- Specialists appointed at the Junior rank must possess a baccalaureate degree in a related science (or equivalent degree) or at least four years of research experience.
- Specialists appointed at the Assistant rank must possess a master’s degree (or equivalent degree) or a baccalaureate degree (or equivalent degree) with three or more years of research experience.
- Specialists appointed at the Associate rank must possess a master’s degree (or equivalent degree) or five to ten years of research experience.
- Specialists appointed at the Full rank must possess a terminal degree (or equivalent degree) or ten or more years of research experience.
- Knowledge and experience with magnetic resonance imaging (MRI) or spectroscopy (MRS) technology.
- Applicants must meet all the qualifications by the time of hire.
- Applicant materials must list current and/or pending qualifications upon submission.
Preferred Qualifications:
- Ability to work with mouse models
- Candidates with a hyperpolarized 13C MRI or other MRI based metabolic imaging background -Candidates with fervent interest in metabolism and its implication in diseases like cancer are encouraged to apply
- Familiarity with computational tools (e.g. MATLAB, Linux, Python, R, PRISM)
- Hands-on experience of mouse tumor models
- Familiarity with biochemical and molecular assays
See Table 24B for the salary range for this position. A reasonable estimate for this position is $53,100-$188,200.
Please apply online at: https://aprecruit.ucsf.edu/JPF05376 with a cover letter and CV.
Vascular and Cardiac Biology
Junior Specialist – Huang Lab
The Huang Lab in the Cardiovascular Research Institute at University of California, San Francisco is seeking a Junior Specialist. The candidate will be responsible for designing experiments, analyzing cardiomyocyte proliferation and regeneration, and gene function tests using adenoviral vectors.
Specialists appointed at the junior rank must possess a baccalaureate degree (or equivalent degree) by June 2025 or at least four years of research experience. Applicant’s materials must list (pending) qualifications upon submission.
Appointees in the Specialist series will be expected to engage in specialized research, professional activities and do not have teaching responsibilities. Specialists are expected to use their professional expertise to make scientific and scholarly contributions, and may participate in University and Public Service. Screening of applicants will begin immediately and will continue as needed throughout the recruitment period. Salary and rank will be commensurate with the applicants experience and training.
See Table 24B for the salary range for this position. A reasonable estimate for this position is $53,100 - $56,600.
Please apply online at https://aprecruit.ucsf.edu/JPF05563, with a CV and Cover Letter (include your career plan and a link to the LinkedIn profile, if available).
Junior Specialist - Buchwalter Lab
The Buchwalter laboratory seeks a Junior Specialist to join the team at the Cardiovascular Research Institute on UCSF’s Mission Bay campus. We are working to understand the function and dynamic regulation of the nuclear lamina, which is a structure found at the edge of most eukaryotic nuclei that strengthens the nucleus and influences genome organization and gene expression. Our interest is motivated by hints that the lamina is essential for normal development, and by the existence of a group of rare diseases known as “laminopathies” that are linked to mutations in the Lamin proteins.
Our mission is to make meaningful contributions to science while fostering an inclusive laboratory culture that values both individual growth and effective teamwork. We believe that making scientific discoveries requires the audacity to question existing knowledge and the confidence to explore the unknown. “Success” to us means empowering each lab member to discover. We welcome, respect, and advocate for members across the spectra of race, gender, and socioeconomic class. We embrace cultural differences and recognize that a diversity of perspectives makes for a stronger, more creative team. Applicants can learn more about current team members and projects at Buchwalter Lab.
The Junior Specialist will work under the guidance of the Principal Investigator (Abby Buchwalter) and will perform two major roles: laboratory management (~30%) and experimental work (~70%).
The Buchwalter lab is a team of ~8 students and postdocs. The Specialist will maintain basic laboratory organization to support the team by performing functions including: placing orders, ensuring that laboratory databases are kept up to date, maintaining basic equipment, and maintaining the lab’s compliance with UCSF safety standards. We are a well-organized group with existing databases, order records, and equipment maintenance logs to ease this workload.
The Specialist will have the opportunity to take a leadership role in an ongoing project that will involve experimental workflows such as:
- Molecular biology and biochemistry: RNA and DNA extractions, cloning, mutagenesis, quantitative PCR, protein immunoprecipitations, Western blotting, and proteomic sample preparation
- Next generation sequencing workflows: library preparation, RNAseq, ATAC-seq, ChIP-seq, Cut-and-Run
- Bioinformatic workflows for analysis of next generation sequencing and/or proteomic data
- Stem cell culture: CRISPR editing, stem cell culture, directed differentiation, and fluorescence microscopy of human induced pluripotent stem cells (hiPSCs)
Candidates for the Junior Specialist rank must possess (or in process of obtaining) a Bachelor’s degree in the Life Sciences or related field with at least six months of experience working in biology laboratory. Applicants must have obtained the degree requirement for the Specialist rank by the time of hire. Applicant’s materials must list (pending) qualifications upon submission. The ideal candidate would have experience with some of the techniques listed above. However, we value curiosity, creativity, strong analytical and organizational skills, and the motivation to work both independently and to support the goals of the team above specific technical experience.
See Table 24B for the salary range for this position. A reasonable estimate for this position is $51,300 - $54,600.
We ask applicants to apply online at https://aprecruit.ucsf.edu/JPF04960 with a short cover letter describing your background and interests, a CV, and contact information for 2 references. Informal inquiries to Dr. Abby Buchwalter are welcome ([email protected]) but formal applications must be submitted through AP Recruit.